Protein Alignment CG5790 and hsk1

DIOPT Version :10

• Sequence 1: NP_609876.2
• Gene: CG5790 / 35095
• FlyBaseID: FBgn0032677
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_596328.1
• Gene: hsk1 / 2541165
• PomBaseID: SPBC776.12C
• Length: 507
• Species: Schizosaccharomyces pombe
• Alignment Length: 560
• Identity: 143/560 - (25%)
• Similarity: 214/560 - (38%)
• Gaps: 189/560 - (33%)

  Fly    90 APKCT----ADLNE--KLVKINRQNANKE-----LSTIQAKDMQSVDKNEEALKELQESIPEINK 143
            :||.|    .|::.  ::.:::.:|.|:.     :..|.|:|.:.::.......||||:...|.|
pombe     9 SPKVTHEQQTDIDSECEITEVDDENVNENKSQEMIQDIPARDREEIENITRTFVELQENYRLIEK 73

  Fly   144 IFDVHCRIGSGTFSTVLL----------------------GTLQRERGLVETQRRR---FAIKHH 183
                   ||.||||:|..                      .:..:|:..|....|:   .|||..
pombe    74 -------IGEGTFSSVYKAEDLHYGRYINDWDIQSEVLKESSFGKEKIPVNEDSRKPKYVAIKKI 131

  Fly   184 NPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDY 248
            ..|:.|.||..|||.:|.:.|...:..:...:|..|.|..::||..|..|...|.:.::.::..|
pombe   132 YATSSPARIYNELEILYLLRGSSVIAPLITALRNEDQVLVVLPYYEHTDFRQYYSTFSYRDMSIY 196

  Fly   249 LRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQRIADDGSVVQSSDLSSREVFS 313
            .|.|..|::......:||||:||||.|::.||...:|.|||||:|.  ||.
pombe   197 FRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLAERY--DGR-------------- 245

  Fly   314 ILRDLENGRSVTLTDGNSAQAEAEDYMARRRMRALGGGGSVERAVTGPPSIQKLREQAGGHLTKK 378
                 :...|...|:.|:|:. |.|:                       ||  .:|.:.|:: |.
pombe   246 -----QQSHSCRCTNSNAAEL-AHDF-----------------------SI--AQETSLGYI-KN 278

  Fly   379 DVANQRADTMRLLNRLRLVSPNADPNNYVVSTNTSKKEMHASRAGTPGYRPPEVLLRYPKQSTAV 443
            |                              |..||:   |:||||.|:|.||||.:...||..|
pombe   279 D------------------------------TRPSKR---ANRAGTRGFRAPEVLFKCSSQSPKV 310

  Fly   444 DVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLAQKVNTLDLRR 508
            |:|:||||:||.|:...|.|.:..|..||.||..:||...:|:.|.|  ........|:||..:|
pombe   311 DIWSAGVILLSFLTKRFPMFNSKDDVDALMEIACIFGKSEMRQCAAL--HGCTFETNVSTLTEKR 373

  Fly   509 VCMR-----------------FRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHN 556
            |..|                 .||              :|.....:|
pombe   374 VNFRKLILWASCGSASIYKEKLRH--------------KPSQEERLC------------------ 406

  Fly   557 LERYDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPF 596
                          .|.|.:.||::..|||:|||||.|.|
pombe   407 --------------LDFLEKCLELDCNKRISAEEALDHDF 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5790	NP_609876.2	STKc_Cdc7	143..597	CDD:270921	129/496 (26%)
		Protein Kinases, catalytic domain	<238..>363	CDD:473864	30/124 (24%)
		Protein Kinases, catalytic domain	<427..597	CDD:473864	53/187 (28%)
hsk1	NP_596328.1	STKc_Cdc7	66..433	CDD:270921	131/503 (26%)