Protein Alignment Ptp36E and ptprua

DIOPT Version :9

• Sequence 1: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_005159609.1
• Gene: ptprua / 563584
• ZFINID: ZDB-GENE-060503-232
• Length: 1478
• Species: Danio rerio
• Alignment Length: 571
• Identity: 182/571 - (31%)
• Similarity: 307/571 - (53%)
• Gaps: 36/571 - (6%)

  Fly   123 KNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLL------KPNAYIVTQGPVEETV 181
            |.:..|.::...:..|.:||.:..:....:||||||:|:|..:      :.|.:|.||||.::.:
Zfish   919 KKDKTKGRHDTLLGQDRHRVKMHSLLADPNSDYVNANYIDIRINREGYQRSNHFIATQGPKQDMI 983

  Fly   182 QAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFR 246
            ..:||||||||..:|||:||..:..::.|.:|||.:.|:   ||||.|.:::.|.||.:.:|||.
Zfish   984 YDFWRMVWQENCYSIVMITKLVEVGRMKCCKYWPDDSEL---YGDIKITLLKTETLAEYTVRTFA 1045

  Fly   247 LYKMNEKQEVTDERLILQFHYTEWYSHSCPF-SNALLEFRRRVRLVVGNIIKDEDDMRGPILVHC 310
            :    |::....:..:.|||:|.|..|..|: :..||.|.|||:       .......||::|||
Zfish  1046 M----ERRGYPAKHEVCQFHFTSWPEHGVPYHATGLLAFLRRVK-------ASTPPDAGPVVVHC 1099

  Fly   311 SDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKT 375
            |.|.||:|.|:.:|..|::||.|...:::..:|.|...|..:::..|||.||:|.:.|..:||:|
Zfish  1100 SMGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCGET 1164

  Fly   376 WFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPP 440
            ..|::|.....|.....:|.|..::.:.|:..:...||...:.:|:......||||||.:..:||
Zfish  1165 AIPITEFGLSYKDMLSVDSQTNTSQLREEFQTLNSVTPHLDVEECSVSLLPRNREKNRSMDVLPP 1229

  Fly   441 DNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQP 505
            |....:|.|.:|:. .:|||:..:|.:.:|..::||..|:..|..:||.||:|..|:::|:|.|.
Zfish  1230 DRALAFLVSNEGDG-NNYINAALMDSFLQPAAFVVTPHPLPTTTTDFWRLVFDYGCTSIVMLNQL 1293

  Fly   506 PSQSQQYP--SFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPTR 568
            ...:..:|  .:|| ::.|::|||: :|..:...:..|:....|::|.......|.:....|.:|
Zfish  1294 NQSNSAWPCLQYWP-ETGMQQYGPM-TVELLSRSTDENVVTRLFRVNNITRDPRENLPCWNADSR 1356

  Fly   569 ----------TVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPDGRSRAGV 623
                      .|:.||...|....::|.|..:.:.|:..|:.|:.:...|...|...:|..|:|.
Zfish  1357 IPKKLQEGHLVVRHFQFLRWSAYREIPDSKKAFLNLLAQVQKWQRECGDGRTIVHCLNGGGRSGT 1421

  Fly   624 YCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674
            :||....:|.|..|..||||.||||:|..:|.:||:|.:|::||:|.|.|:
Zfish  1422 FCACTMIMEMVHHHNMVDVFYAVKTLRNSKPNMVESMEQYRFCYELALEYL 1472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	86/249 (35%)
		Y_phosphatase	428..671	CDD:395053	80/254 (31%)
ptprua	XP_005159609.1	MAM	26..186	CDD:279023
		MAM	26..184	CDD:99706
		I-set	188..281	CDD:254352
		FN3	285..356	CDD:214495
		FN3	385..485	CDD:238020
		FN3	494..589	CDD:238020
		Y_phosphatase	922..1157	CDD:278528	86/248 (35%)
		PTPc	934..1157	CDD:238006	85/236 (36%)
		PTPc	1189..1470	CDD:214550	84/283 (30%)
		PTPc	1219..1470	CDD:238006	78/253 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4517
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D20096at33208
OrthoFinder	1	1.000	-	-		FOG0000829
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.780