Protein Alignment Ptp36E and ptprz1b

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_073803012.1
• Gene: ptprz1b / 553019
• ZFINID: ZDB-GENE-050506-100
• Length: 1457
• Species: Danio rerio
• Alignment Length: 705
• Identity: 187/705 - (26%)
• Similarity: 324/705 - (45%)
• Gaps: 112/705 - (15%)

  Fly    30 DVEKQQRKSRAIVSIPNTIKLSMLNSGLL-----SFERIKLEARDENNSLSKTIPNGP------- 82
            :.||:.....||||....:.|.:| .|:|     .|:.......|.|::.:.:.|:.|
Zfish   775 ETEKRAVVPLAIVSTLTVLCLVVL-VGILIYWRRCFQTAHFYVEDTNSARAISAPSTPLLLPTED 838

  Fly    83 ---IDIRHFLK-LCDL--RRKFPVLYKLEFQTAAKVESNTCRHAL------KKNNLEKNQNPKCI 135
               :.::.|:| :.||  ..||...:::..::..:::..|....:      ..:|..||:....:
Zfish   839 NEALPVKDFVKHVADLHANHKFSKEFEILKESYEEIQGCTADMGITTDSSNHPDNKSKNRYINIL 903

  Fly   136 PYDYNRVVL----EKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAI 196
            .||::||.|    :|.|  :..||:||:|||...:|.|||..|||::.:::.:|||:|::|:..|
Zfish   904 AYDHSRVKLSQNSDKDG--KTGDYINANYVDGFNQPKAYIAAQGPLKGSLEDFWRMIWEQNVGVI 966

  Fly   197 VMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRL----YKMNEKQEVT 257
            ||:|...:..:..|.||||  :|..|.||...:.:.....||.:.:|||.|    .|...::..:
Zfish   967 VMITNLVEKGRRKCDQYWP--LENQEDYGCFLVTLKSSRTLAYYTLRTFTLRNVQIKKGSQKGRS 1029

  Fly   258 DERLILQFHYTEWYSHSCP-FSNALLEFRRRVRLVVGNIIKDEDDMR----GPILVHCSDGGGRS 317
            .||.:|.||||:|.....| ::..||.|           |:.....|    ||::||||.|.||:
Zfish  1030 QERTVLHFHYTQWPDMGVPEYTLPLLSF-----------IRTSSQARTAEMGPVVVHCSAGVGRT 1083

  Fly   318 GVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSEL 382
            |.|:.||:.|:..:||...|:.|:||.:|..|..||:..|||.||:|.|.|.|...:|....|.:
Zfish  1084 GTYIVIDSMLKQIKEENTVNIMGFLKHIRTQRNYLVQTEEQYVFIHDALVEAIRSKETLVSSSLI 1148

  Fly   383 SDRLKAKARRNSGTKM---NEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFR 444
            ...:..........|.   .:::.......||:      |.....:..|..|||....:|.:..|
Zfish  1149 HTYVSGLLTPGPAGKTPLEKQFKLVSQSCAKQS------DYTTALKESNVSKNRTACLMPVERSR 1207

  Fly   445 PYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQPPSQS 509
            ..|::..|.: :||||:.::.|:.:.||:|||:.|:.:|:.:||.:::|.....:|.|....:.|
Zfish  1208 VSLSAAAGES-SDYINASYLLGFHQSREFIVTQNPLPNTIHDFWRMIWDHNTQIIVSLPDTHNMS 1271

  Fly   510 QQYPS-FWPNKSK------------------MEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVS 555
            .:... :||.|.:                  :....||...|:::..    :|. ::.:.
Zfish  1272 SEAECVYWPTKDEPISCETFTVSFRDEDSLNLSNEEPVLVQHFILEA----LKD-DYVLE----- 1326

  Fly   556 LTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVY-LMNMVEIWRNKVDYGPVCVVSPDGRS 619
                          |..||...||    .|.|..|..: |:|::....::.: |||.:....|.|
Zfish  1327 --------------VHQFQSPRWP----DPDSPISNCFELINIIREESSRRE-GPVLIHDGCGGS 1372

  Fly   620 RAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674
            .||::||....:.|:.:...|||:|..:.:...||.:..::.:|::.|..:|..|
Zfish  1373 SAGLFCALVTLVNQLDEENSVDVYQTARMINLMRPGVFNDVEQYQFLYKAILSLV 1427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	94/255 (37%)
		Y_phosphatase	428..671	CDD:459674	61/262 (23%)
ptprz1b	XP_073803012.1	None