Protein Alignment Ptp36E and Ptp99A

DIOPT Version :9

• Sequence 1: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 169/574 - (29%)
• Similarity: 286/574 - (49%)
• Gaps: 63/574 - (10%)

  Fly   117 CRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDS-DYVNASYVDSLLKPNAYIVTQGPVEET 180
            |.|:....|..||:......||::||.|....|.:.: ||:||:::|...|.:|:|.||||:.:|
  Fly   665 CEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDT 729

  Fly   181 VQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTF 245
            ...:|||:|::.::.|||:|...:..:..|..|||  .:..|.||.|.:.::.||.::.:.:||.
  Fly   730 FDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP--KDGVETYGVIQVKLIEEEVMSTYTVRTL 792

  Fly   246 RL--YKMNEKQEVTDERLILQFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDEDDMR----G 304
            ::  .|:.:|::...|:|:.|:|||.|..|..|..          .|.|.|.:|......    |
  Fly   793 QIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDH----------PLPVLNFVKKSSAANPAEAG 847

  Fly   305 PILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEH 369
            ||:||||.|.||:|.|:.:||.|:..:::...||||:|:.:|..|..||:..|||.|::|.|.|.
  Fly   848 PIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA 912

  Fly   370 IICGKTWFPVSELSDRLKAKARRNSGTKMNEY-QAEYDQICKQTPRFTIGDCAGGHRADNREKNR 433
            |..|:|.. ::|..:.||         ....| :.:|..|.:..|:..  ..|...:..|..|||
  Fly   913 IASGETNL-MAEQVEELK---------NCTPYLEQQYKNIIQFQPKDI--HIASAMKQVNSIKNR 965

  Fly   434 DVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSA 498
            ..: .|.:..|.:||...|...:||||:.::.|:.:.|::|||:.||.||:.:||.:|:|.....
  Fly   966 GAI-FPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQT 1029

  Fly   499 VVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKK-IVSLTEMMAG 562
            ||:|..  .....:..|||:::.     |:.|.||.:  .:.|      |.||. .||...::..
  Fly  1030 VVLLSS--LDDINFAQFWPDEAT-----PIESDHYRV--KFLN------KTNKSDYVSRDFVIQS 1079

  Fly   563 VKAPTR-TVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDY--GPVCVVSPDGRSRAGVY 624
            ::.... ||::.....||    ..|:.||:...  :|::.....||  ||:.:|...|.::|..:
  Fly  1080 IQDDYELTVKMLHCPSWP----EMSNPNSIYDF--IVDVHERCNDYRNGPIVIVDRYGGAQACTF 1138

  Fly   625 CAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYVLHFL 678
            ||.::...::......:|:|..|.....||.:..:..:.:     |::.:|.||
  Fly  1139 CAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIR-----VIYNILSFL 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	87/249 (35%)
		Y_phosphatase	428..671	CDD:395053	64/246 (26%)
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		fn3	249..331	CDD:278470
		FN3	342..437	CDD:238020
		FN3	442..520	CDD:238020
		PTPc	646..911	CDD:214550	89/257 (35%)
		PTPc	676..911	CDD:238006	86/246 (35%)
		PTPc	935..1186	CDD:214550	70/279 (25%)
		PTPc	963..1169	CDD:238006	62/227 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010