Protein Alignment Ptp36E and Ptp69D

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_524048.2
• Gene: Ptp69D / 39443
• FlyBaseID: FBgn0014007
• Length: 1462
• Species: Drosophila melanogaster
• Alignment Length: 654
• Identity: 179/654 - (27%)
• Similarity: 313/654 - (47%)
• Gaps: 74/654 - (11%)

  Fly    59 SFERIKLEARDENNSLSKTIPN------GPIDIRHFLKLCDLRRKFPVLYK-------LEFQTAA 110
            |..|.....|:.|:|...|..|      |||   |.|   ||...:...:|       .|::...
  Fly   843 SLSRALFGRRNHNHSHFITSGNHKGFDAGPI---HRL---DLENAYKNRHKDTDYGFLREYEMLP 901

  Fly   111 -KVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQ 174
             :....|.:::..|.|..||:.|....||..||.|..:.|||.:||:||::|....:...:|..|
  Fly   902 NRFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVINGLQTTDYINANFVIGYKERKKFICAQ 966

  Fly   175 GPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLAN 239
            ||:|.|:..:|||:|::::..|||||...::.|..|.:|||..:...:|:|||.:...:|.:..:
  Fly   967 GPMESTIDDFWRMIWEQHLEIIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQERKTGD 1031

  Fly   240 FHIRTFRLYKMNEKQ--EVTDERLILQFHYTEWYSHSCP-FSNALLEFRRRVRLVVGNIIKDEDD 301
            :..||..:.| |:..  |..|.|.|.|:||..|.....| ..:.:::|.|::..|...
  Fly  1032 YIERTLNVSK-NKANVGEEEDRRQITQYHYLTWKDFMAPEHPHGIIKFIRQINSVYSL------- 1088

  Fly   302 MRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTL 366
            .|||||||||.|.||:|..:::|:.::..|||:..:::..:..||..|..||::::||.|:|..|
  Fly  1089 QRGPILVHCSAGVGRTGTLVALDSLIQQLEEEDSVSIYNTVCDLRHQRNFLVQSLKQYIFLYRAL 1153

  Fly   367 EEHIICGKTWFPVSELSDRLKA-KARRNSG-----TKMNEYQAEYDQICKQTPRFTIGDCAGGHR 425
            .:....|.|...:..::..::: |.:.|.|     .:..:..|..|:|.|        .|:.|..
  Fly  1154 LDTGTFGNTDICIDTMASAIESLKRKPNEGKCKLEVEFEKLLATADEISK--------SCSVGEN 1210

  Fly   426 ADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSL 490
            .:|..|||....:|.|..|..||.......:.|||:.|::||.....:|:.:.|:::|:|:||.:
  Fly  1211 EENNMKNRSQEIIPYDRNRVILTPLPMRENSTYINASFIEGYDNSETFIIAQDPLENTIGDFWRM 1275

  Fly   491 VYDQECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKI-NKKIV 554
            :.:|..:.:|::.:.....::.|.:|.:..  .:|..:. |.||.|:|.....:.||.: |.||
  Fly  1276 ISEQSVTTLVMISEIGDGPRKCPRYWADDE--VQYDHIL-VKYVHSESCPYYTRREFYVTNCKI- 1336

  Fly   555 SLTEMMAGVKAPTRTVQLFQLTCWP-MGHKVPSSTNSLVYLMNMV-EIWRNKVDYG---PVCVVS 614
                      ..|..|..||...|| :..:||.....::.|::.. ..::|..:.|   |:.|..
  Fly  1337 ----------DDTLKVTQFQYNGWPTVDGEVPEVCRGIIELVDQAYNHYKNNKNSGCRSPLTVHC 1391

  Fly   615 PDGRSRAGVYCAANACIEQVIQHGE----VDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV- 674
            ..|..|:.::.|  .||  ::||..    ||:....:.:|..|..|:.:..:|::.:..:::|.
  Fly  1392 SLGTDRSSIFVA--MCI--LVQHLRLEKCVDICATTRKLRSQRTGLINSYAQYEFLHRAIINYSD 1452

  Fly   675 LHFL 678
            ||.:
  Fly  1453 LHHI 1456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	85/245 (35%)
		Y_phosphatase	428..671	CDD:459674	62/252 (25%)
Ptp69D	NP_524048.2	Ig_3	35..114	CDD:464046
		Ig_3	134..216	CDD:464046
		fn3	237..321	CDD:394996
		FN3	<300..>524	CDD:442628
		PTPc	892..1155	CDD:214550	88/270 (33%)
		PTPc	1186..1449	CDD:214550	68/288 (24%)