Protein Alignment Ptp36E and Ptprk

DIOPT Version :9

• Sequence 1: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001025073.2
• Gene: Ptprk / 360302
• RGDID: 619706
• Length: 1439
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 210/598 - (35%)
• Similarity: 326/598 - (54%)
• Gaps: 40/598 - (6%)

  Fly    89 LKLCDLRRKFPVL-------YKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEK 146
            :::.||.:...::       :|.|:::..:.:|.:...|.|..|..||:....|.||::||:|:.
  Rat   867 IRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQP 931

  Fly   147 VGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCH 211
            |.....|||:||:|:|...:|:.||.|||||.|||..:|||||||..:.|||:|...:..:|.|:
  Rat   932 VEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWRMVWQEQSACIVMVTNLVEVGRVKCY 996

  Fly   212 QYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCP 276
            :|||.:.||   |||..:..|..|.||.:.:|||.|    |::...:.|.:.|||:|.|..|..|
  Rat   997 KYWPDDTEV---YGDFKVTCVEMEPLAEYVVRTFTL----ERRGYNEIREVKQFHFTGWPDHGVP 1054

  Fly   277 F-SNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFG 340
            : :..||.|.|||:|       ......|||:||||.|.||:|.|:.||..|::||.|...:::.
  Rat  1055 YHATGLLSFIRRVKL-------SNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYN 1112

  Fly   341 YLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEY 405
            .:|.||..|..:|:..|||.||:|.:.|..:||:|..||.|.........|.:|.|..:..:.|:
  Rat  1113 CVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEF 1177

  Fly   406 DQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKP 470
            ..:...|||....||:......|.:|||.:..:|||...|:|.:..|.: ::|||:..:|.|.:|
  Rat  1178 QTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDSYRQP 1241

  Fly   471 REYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVM 535
            ..:|||::|:.:|:.:||.||||..|:::|:| .....||..|.:||.:. |.:|||: .|..:.
  Rat  1242 AAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPEEG-MLRYGPI-QVECMS 1303

  Fly   536 SKSYTNIKQWEFKINK--KIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMV 598
            .....::      ||:  :|.:||....|.    ..||.||...|....:||.|..|.:.|:..|
  Rat  1304 CSMDCDV------INRIFRICNLTRPQEGY----LMVQQFQYLGWASHREVPGSKRSFLKLILQV 1358

  Fly   599 EIWRNKVDYGP--VCVVSPDGRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMT 661
            |.|:.:.:.|.  ..:...:|..|:|::||....:|.|.:...||||.||||:|..:|.:||...
  Rat  1359 EKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPE 1423

  Fly   662 EYKYCYDLVLHYV 674
            :|::|||:.|.|:
  Rat  1424 QYRFCYDVALEYL 1436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	102/243 (42%)
		Y_phosphatase	428..671	CDD:395053	83/246 (34%)
Ptprk	NP_001025073.2	MAM	31..191	CDD:214533
		MAM	35..191	CDD:99706
		IG_like	201..287	CDD:214653
		Ig	203..283	CDD:299845
		fn3	293..371	CDD:278470
		FN3	487..588	CDD:238020
		PTPc	886..1140	CDD:214550	107/267 (40%)
		PTPc	913..1140	CDD:238006	101/240 (42%)
		Y_phosphatase	1200..1434	CDD:278528	83/247 (34%)
		PTPc	1202..1434	CDD:238006	82/245 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D20096at33208
OrthoFinder	1	1.000	-	-		FOG0000829
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820