DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp36E and Y71G12B.31

DIOPT Version :9

Sequence 1:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001293450.1	Gene:	Y71G12B.31 / 3565511	WormBaseID:	WBGene00044348	Length:	423	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	89/298 - (29%)
Similarity:	142/298 - (47%)	Gaps:	43/298 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LRRKFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNA 158
            |:.:|.||.:.|.:...:......|||      ..|:....:|||:..|.|:      ..||:||
Worm   141 LQDEFLVLSRTEARRLTRSTDRATRHA------AANRYSDIVPYDHTLVELD------TGDYINA 193

  Fly   159 SYVDSLLKPNAYIVTQGPVE-------ETVQAYWRMVWQENISAIVMLTK-TFDFAKVMCHQYWP 215
            |:|........:|.||||::       |||..:|||:.|.:::.||||.: ..||.: .|.:|||
Worm   194 SFVQGESDATRWIATQGPIDSGECIGKETVSDFWRMIVQYDVACIVMLGQHQEDFVQ-KCGEYWP 257

  Fly   216 PNMEVHEQYGDIFINIVREEQLANFHIRTFRL---------YKMNEKQEVTDER---LILQFHYT 268
            ..|...|:||::.:.:|.|.:...:..|.|.:         .|.:.|...:.::   .:.|:.|.
Worm   258 SAMGKTERYGEVDVKLVCELEEKTWVHREFDVSPTSSYSSSTKSSRKSRASRQQSHMKVSQWQYK 322

  Fly   269 EWY-SHSCPFSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEE 332
            ||. :...|.....|||..:||   |.      ....||:||||.|.||:||::..|..:...|.
Worm   323 EWKDTGGAPRIANFLEFLLQVR---GR------QYTSPIVVHCSAGIGRTGVFICTDNVISRFES 378

  Fly   333 EECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHI 370
            |...::|..:.:.||.|..:|..|:||:.|||.:.|::
Worm   379 EGIIDIFSEVNRSRQQRPSMVYTVKQYECIYDIIGEYL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	80/263 (30%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
Y71G12B.31	NP_001293450.1	PTPc	170..414	CDD:238006	80/259 (31%)
Y71G12B.31	NP_001293450.1	Y_phosphatase	170..412	CDD:278528	80/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900