Protein Alignment Ptp36E and ptprub

DIOPT Version :9

• Sequence 1: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_009290693.1
• Gene: ptprub / 335096
• ZFINID: ZDB-GENE-030131-7036
• Length: 1450
• Species: Danio rerio
• Alignment Length: 563
• Identity: 191/563 - (33%)
• Similarity: 310/563 - (55%)
• Gaps: 36/563 - (6%)

  Fly   122 KKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLL------KPNAYIVTQGPVEET 180
            ||.:..|.::...:.||.:||.|..:.|..:|||:||:|:|..:      :.|.:|.||||.:||
Zfish   908 KKKDKTKGRHDTLMGYDRHRVKLHPLLGDPNSDYINANYIDIRINREGYHRSNHFIATQGPKQET 972

  Fly   181 VQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTF 245
            |..:||||||||..:|||:||..:..:|.|.:|||   :..|.||||.|.:::.|.||.:.:|||
Zfish   973 VYDFWRMVWQENCFSIVMITKLVEVGRVKCCKYWP---DESEMYGDIKITLLKTETLAEYTVRTF 1034

  Fly   246 RLYKMNEKQEVTDERLILQFHYTEWYSHSCPF-SNALLEFRRRVRLVVGNIIKDEDDM-RGPILV 308
            .|    |::..:.:..:.|||:|.|..|..|: :..||.|.|||        |....: .||::|
Zfish  1035 AL----ERRGYSAKHEVCQFHFTSWPEHGVPYHATGLLAFIRRV--------KTSTPLDAGPVVV 1087

  Fly   309 HCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICG 373
            |||.|.||:|.|:.:|..|::||.|...:::..:|.|...|..:::..|||.||:|.:.|..:||
Zfish  1088 HCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCG 1152

  Fly   374 KTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCV 438
            :|..||:|.:...|...|.:|.:..::.:.|:..:...||...:.:|:......||||||.:..:
Zfish  1153 ETAIPVNEFALAYKEMLRVDSQSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVL 1217

  Fly   439 PPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSAVVVLC 503
            |||....:|.:.:|.: .:|||:..:|.:.:|..:|||..|:..|..:||.||:|..|::||:|.
Zfish  1218 PPDRALAFLVTTEGES-NNYINAALMDSFHRPAAFIVTPHPLPGTTSDFWRLVFDYGCTSVVMLN 1281

  Fly   504 QPPSQSQQYP--SFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAP 566
            |....:..:|  .:||... :::|||: .|.::...:..:|....|::.    ::|.:..|
Zfish  1282 QLNQSNSAWPCVQYWPEPG-LQQYGPM-QVEFLSMSADEDIITRLFRVK----NVTRLQEG---- 1336

  Fly   567 TRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPDGRSRAGVYCAANACI 631
            ...|..||...|.....||.|..:.:.|:..|:.|:.:...|...|...:|..|:|.|||:|..:
Zfish  1337 QLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQRECGEGRTVVHCLNGGGRSGTYCASNILM 1401

  Fly   632 EQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674
            |.:.....||||.||||:|..:|.:||.:.:|::||:|||.|:
Zfish  1402 EMIQYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYL 1444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	94/250 (38%)
		Y_phosphatase	428..671	CDD:395053	78/244 (32%)
ptprub	XP_009290693.1	MAM	26..184	CDD:279023
		MAM	26..182	CDD:99706
		IG_like	192..278	CDD:214653
		FN3	282..353	CDD:214495
		FN3	384..480	CDD:238020
		FN3	489..584	CDD:238020
		Y_phosphatase	912..1147	CDD:278528	94/249 (38%)
		PTPc	923..1147	CDD:238006	93/238 (39%)
		PTPc	1179..1442	CDD:214550	83/273 (30%)
		PTPc	1209..1442	CDD:238006	77/243 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4517
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D20096at33208
OrthoFinder	1	1.000	-	-		FOG0000829
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920