DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp36E and pyp2

DIOPT Version :9

Sequence 1:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_594899.1	Gene:	pyp2 / 2542200	PomBaseID:	SPAC19D5.01	Length:	711	Species:	Schizosaccharomyces pombe

Alignment Length:	314	Identity:	88/314 - (28%)
Similarity:	143/314 - (45%)	Gaps:	41/314 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 SKTIPNGPIDIRHFLKLCDLRRKFPVLYKLEFQTAAKV---ESNTCRHALKKNN--LEKNQNPKC 134
            :|.:...|.::...|....:..||..|.::|...:...   :|:.|..|..::.  ..||:....
pombe   403 AKKVSPPPCEVLADLNTASIFYKFKRLEEMEMTRSLAFNDSKSDWCCLASSRSTSISRKNRYTDI 467

  Fly   135 IPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQEN--ISAIV 197
            :|||..||.|....|.  |||:|||::|  :....||..|.|...|:..:|.|||..:  ...||
pombe   468 VPYDKTRVRLAVPKGC--SDYINASHID--VGNKKYIACQAPKPGTLLDFWEMVWHNSGTNGVIV 528

  Fly   198 MLTKTFDFAKVMCHQYWPPNMEVHE--QYGDIFINIVREEQLANFHIRT--FRLYKMNEKQEVTD 258
            |||..::.....|.||||.|.: |.  ..|.:.|::.:.|...:..:.|  |||.|.|     ..
pombe   529 MLTNLYEAGSEKCSQYWPDNKD-HALCLEGGLRISVQKYETFEDLKVNTHLFRLDKPN-----GP 587

  Fly   259 ERLILQFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSI 323
            .:.|..|....|:..:.|...::....|.:         |:....||:.||||.|.||:|.::::
pombe   588 PKYIHHFWVHTWFDKTHPDIESITGIIRCI---------DKVPNDGPMFVHCSAGVGRTGTFIAV 643

  Fly   324 DANLEL----------AEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLE 367
            |..|::          .|:.:.| :|..:..||..|..:|:|.||:||:||.::
pombe   644 DQILQVPKNILPKTTNLEDSKDF-IFNCVNSLRSQRMKMVQNFEQFKFLYDVVD 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	78/261 (30%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
pyp2	NP_594899.1	DSP_MapKP	4..129	CDD:238723
		COG5599	405..709	CDD:227886	87/312 (28%)
		PTPc	461..697	CDD:238006	78/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100