Protein Alignment Ptp36E and Ptpn1

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_036769.1
• Gene: Ptpn1 / 24697
• RGDID: 61965
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 119/500 - (23%)
• Similarity: 191/500 - (38%)
• Gaps: 150/500 - (30%)

  Fly    84 DIRHFLKLCDLRRKFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVG 148
            ||||  :..|    ||                 ||.|....|..:|:.....|:|::|:.|.:
  Rat    22 DIRH--EASD----FP-----------------CRIAKLPKNKNRNRYRDVSPFDHSRIKLHQ-- 61

  Fly   149 GLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQY 213
              :|:||:|||.:.......:||:||||:..|...:|.|||::....:|||.:..:...:.|.||
  Rat    62 --EDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQY 124

  Fly   214 WPPNMEVHEQYGD--IFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCP 276
            ||...|....:.|  :.:.::.|:..:.:.:|...|    |.....:.|.||.||||.|.....|
  Rat   125 WPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLEL----ENLATQEAREILHFHYTTWPDFGVP 185

  Fly   277 FSNA-LLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEE---CFN 337
            .|.| .|.|..:|| ..|::..:    .|||:||||.|.||||.:...|..|.|.::.:   ..:
  Rat   186 ESPASFLNFLFKVR-ESGSLSPE----HGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVD 245

  Fly   338 VFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQ 402
            :...|.::|:.|.||::..:|.:|.|..:.|                          |.|
  Rat   246 IKKVLLEMRRFRMGLIQTADQLRFSYLAVIE--------------------------GAK----- 279

  Fly   403 AEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGY 467
                        |.:||  ...:...:|.:.:.|..||::..|
  Rat   280 ------------FIMGD--SSVQDQWKELSHEDLEPPPEHVPP---------------------- 308

  Fly   468 TKPREYIVTEWPMKHTL-------GEFWS---LVYDQECSAVVVLCQPPSQSQQYPSFWPNKSKM 522
             .||       |.|.||       .|.:|   .|.::.|....:|.:..|::
  Rat   309 -PPR-------PPKRTLEPHNGKCKELFSNHQWVSEESCEDEDILAREESRA------------- 352

  Fly   523 EKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPT 567
                |..:||.:.|.|.      :.::.|::|......|....||
  Rat   353 ----PSIAVHSMSSMSQ------DTEVRKRMVGGGLQSAQASVPT 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	76/248 (31%)
		Y_phosphatase	428..671	CDD:459674	26/149 (17%)
Ptpn1	NP_036769.1	PTPc-N1	16..292	CDD:350456	92/350 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..322		10/54 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..402		10/60 (17%)