DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp36E and ZK484.7

DIOPT Version :9

Sequence 1:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_491758.1	Gene:	ZK484.7 / 191327	WormBaseID:	WBGene00022753	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	378	Identity:	83/378 - (21%)
Similarity:	154/378 - (40%)	Gaps:	75/378 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KHRSRSSARYDDVEKQQRKSRAIVSIPNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPNGPI 83
            |.|::.|     .:|.:..|:..|....|.:.......::.|.:         |:|.|    ||
Worm     7 KRRTKKS-----TQKSKEVSQRTVDEGTTAEKKTHRKQIVKFVK---------NALEK----GP- 52

  Fly    84 DIRHFLKLCDLRRKFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVG 148
                    ..||.:|..:.:.......|.......|.  ||   :.::..|:  |:|||   |:.
Worm    53 --------AGLRAEFAAMKRFNDFEKMKAFKEAQEHG--KN---RYKDVGCL--DHNRV---KLH 99

  Fly   149 GLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQY 213
            .....||::|::|.:...|..:|.||.|::::...:|.|..||.:.:|.||....:.....|..|
Worm   100 PPWPHDYIHANFVSTPSNPRRFICTQAPLDKSCADFWYMCLQEKVDSIFMLCNIMEKGAKKCCDY 164

  Fly   214 W----PPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTD-----------ERLIL 263
            :    .|.:|..|:...|   ||:.|......      ::.|...::|:           .:.:.
Worm   165 FACKDKPVLEFEEKGHKI---IVKFESTGKMK------FEKNTDAKITETVFTVEGPGGLAQKVT 220

  Fly   264 QFHYTEWYSHSCPFSN-ALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANL 327
            |:|:.:|.....|.:: |::|...:.|           ..:||.:||||.|.||:|..:.|:..|
Worm   221 QYHWIDWPDRGVPTADMAIVELLAKTR-----------PSKGPTVVHCSAGIGRTGSVVMIEYIL 274

  Fly   328 -ELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPV 379
             :|...::.......|:|:|:.|...::..:||.|::..:..:.: .|..|.|
Worm   275 DQLLGGQQIEETDKILQKIREQRNNSIQTDQQYLFVHQVILNYCL-DKKMFDV 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	60/259 (23%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
ZK484.7	NP_491758.1	Y_phosphatase	80..316	CDD:278528	63/265 (24%)
ZK484.7	NP_491758.1	PTPc	81..316	CDD:238006	62/264 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910