DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp36E and T27A3.5

DIOPT Version :9

Sequence 1:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_491761.3	Gene:	T27A3.5 / 188965	WormBaseID:	WBGene00020841	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	93/355 - (26%)
Similarity:	150/355 - (42%)	Gaps:	86/355 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 NGPIDIRHFLK------LCDLRRKFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYD 138
            |.|| :|.|:|      :..|..:|..| |:|.|...|.::....|.      |||:.......|
Worm    55 NEPI-LRDFVKATIQTGVKQLSTEFLNL-KMETQPCNKPKTGHEGHP------EKNRYKDVYCID 111

  Fly   139 YNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTF 203
            ..|||| |......|||::|::| .:...|.:|.||||.|:||..::|::|||....:|||....
Worm   112 DTRVVL-KWPEDSPSDYIHANWV-KINGANKFICTQGPTEKTVDDFYRLIWQEKAPCVVMLCNIM 174

  Fly   204 DFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLIL----- 263
            :..|..|.||||...:     |.:   |:.:.:|.         .|:.|..:..::.::|
Worm   175 ECGKKKCEQYWPETAD-----GQM---ILMDGKLT---------VKIAEPAKEVEQNILLMKITV 222

  Fly   264 -----------QFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRS 317
                       .:.:..|.....| ...:..||..:||...:          ||:||||.|.||:
Worm   223 IDDKGTSHNFEHWQWKAWPDRGVP-ELPMAVFRLLIRLKTAS----------PIVVHCSAGIGRT 276

  Fly   318 GVYMSIDANLELAEEEECFN----VFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFP 378
            |   || ..||:|..:.|..    :...:|::|..|.|.|:...||.|::..|
Worm   277 G---SI-VGLEIALVKFCAGEKVVLKDIVKEIRNQRHGSVQTDAQYLFMHRVL------------ 325

  Fly   379 VSELSDRLKAKARRNSGTKMNEYQAEYDQI 408
                  ...|:.|:.:..:::.:.||||::
Worm   326 ------LALAENRKITSPELSAFVAEYDKV 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	73/262 (28%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
T27A3.5	NP_491761.3	PTPc	73..326	CDD:214550	81/311 (26%)
T27A3.5	NP_491761.3	PTPc	100..326	CDD:238006	73/277 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910