DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp36E and C33H5.16

DIOPT Version :9

Sequence 1:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_501293.3	Gene:	C33H5.16 / 183190	WormBaseID:	WBGene00016382	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	360	Identity:	80/360 - (22%)
Similarity:	148/360 - (41%)	Gaps:	80/360 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RKSRAIVSIPNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPNGPIDIRHFLKLCDLRRKFPV 100
            :|.|.:.::.:..|......| .:.||.|::.:.....:..|:..|||.:|:
Worm     3 QKRRRLPNLKSKEKAEKSQKG-TNDERQKMQKKQIVQFVQTTLEKGPIGLRN------------- 53

  Fly   101 LYKLEFQTAAKVESNTCRHALKK-NNLEKNQNPKCIPYDYNRVVLEKVGGLQDS----------- 153
                ||            :|:|: |:.:|.|:.| ...|:::...:.||.|.::
Worm    54 ----EF------------NAMKRFNDFDKMQSFK-KAQDHHKNRYKDVGCLDNNRVKLAHPPWPH 101

  Fly   154 DYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYW---- 214
            ||::|::|.:......:|..|.|::.|...:|.|..||.:.||.||....:.....|.:|:
Worm   102 DYIHANFVSTPANAKRFICAQAPLDNTCADFWYMCLQERVEAIFMLCNLMEKGAKKCSEYYATKE 166

  Fly   215 PPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQ-----------FHYT 268
            .|.:..||:  |..|.:..|..      .|.:..|.. |..|.:..||::           :|:.
Worm   167 KPELVFHEK--DQKITVKYEAS------GTVKFVKPT-KAVVKETVLIIEGPGGQVLKTTHYHWI 222

  Fly   269 EWYSHSCPFSN-ALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLE-LAE 331
            :|.....|.:: :::|...:.|           .::|||.||||.|.||:|..:.|:...| |..
Worm   223 DWPDRGVPPADLSIIELLIKAR-----------PLKGPIAVHCSAGIGRTGSVVMIEYMCEQLLN 276

  Fly   332 EEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTL 366
            ..:.......|:|:|:.|...::...||.|::..:
Worm   277 GNQIEETDKILQKIREQRNNSIQTDHQYLFVHQVM 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	63/270 (23%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
C33H5.16	NP_501293.3	Y_phosphatase	76..313	CDD:278528	59/256 (23%)
C33H5.16	NP_501293.3	PTPc	77..313	CDD:238006	59/255 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910