Protein Alignment Ptp36E and ptpn-22

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_500128.2
• Gene: ptpn-22 / 176981
• WormBaseID: WBGene00021507
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 102/373 - (27%)
• Similarity: 173/373 - (46%)
• Gaps: 67/373 - (17%)

  Fly    30 DVEKQQRKS---------RAIVSIPNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPNG-PID 84
            ::::|:.||         ..:...||.:.    ...|:.||       .|....:.|:||| |:.
 Worm    17 EIQEQKPKSPPPPLPTSNPVVKDTPNVVP----TGDLIQFE-------SEEERAATTVPNGNPVI 70

  Fly    85 ----------IRHFLKLCD-------LRRKFPVLYKLE-FQTAAKVESNTCRHALKKNNLEKNQN 131
                      :|.|||..:       |||.:.:..:.| .:..|:..|. |  |:...:..:|:.
 Worm    71 FEKNPAMDGLLREFLKEEEAYTPQDYLRRFYQIRVEQEKLRMEAEYRSE-C--AVAPQHYARNRY 132

  Fly   132 PKCIPYDYNRVVLEKVGGLQDSD----YVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQEN 192
            ...:|||.|||.::|     ||:    |:|||.:........:|..|.|:..|:..:|:|:.:..
 Worm   133 RDILPYDKNRVEIQK-----DSENPEGYMNASLIQLPGGKTEFIAAQAPLPATLDEWWKMIDEHR 192

  Fly   193 ISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVT 257
            :|.:|:|.|..:..|:.|.:|||..:...|.:||..|.: .||:|.:......|..|| |.|...
 Worm   193 VSLVVILCKLVELNKIKCERYWPEQVGESELFGDYEITL-EEEKLFDDDEYLMRCLKM-ENQTTG 255

  Fly   258 DERLILQFHYTEWYSHSCPFSNALLEFRRRVRLV--VGNI---IKDEDDMRGPILVHCSDGGGRS 317
            :.|.:.|.||.||..|.||...     ::.:.::  :.||   :..:|.  .|||||||.|.||:
 Worm   256 ECRKVHQLHYREWPDHGCPSGE-----KQLLNMIDLMENIHEEVSPQDS--SPILVHCSAGVGRT 313

  Fly   318 GVYMSIDANLE--LAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIY 363
            |..::|:...|  .||.....::||.:..||:.|..:|:..:|::|::
 Worm   314 GTIIAINFIREQMKAETLHSIDIFGLVMTLRKQRASMVQTQDQFQFVH 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	76/250 (30%)
		Y_phosphatase	428..671	CDD:459674
ptpn-22	NP_500128.2	PTPc	102..365	CDD:214550	81/277 (29%)