Protein Alignment Ptp36E and Ptp69D

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_061508307.1
• Gene: Ptp69D / 1273859
• VectorBaseID: AGAMI1_008430
• Length: 1471
• Species: Anopheles gambiae
• Alignment Length: 639
• Identity: 164/639 - (25%)
• Similarity: 296/639 - (46%)
• Gaps: 54/639 - (8%)

  Fly    66 EARDENNSLSKTIPNG--PIDIRHFLKLCDLRRKFPVL----------------------YKLEF 106
            ||....:||.:.:.||  .:::.|...|.....|.|||                      ::.||
Mosquito   842 EAISLGDSLRRALCNGGRGVNVHHRHLLGSSSAKPPVLPPISKDDLPKAYNDKHKDSDYGFQHEF 906

  Fly   107 QTAA-KVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAY 170
            :... |....|.:::..|.|:.||:.|....||..||.|..:.||..|||:||::|....:...:
Mosquito   907 ELLPDKFADRTTKNSDMKENMPKNRYPDIKAYDQTRVKLTPLNGLAGSDYINANFVIGYKERKKF 971

  Fly   171 IVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREE 235
            |..|||::.|:..:|||:|::::..|||||...::.|..|.:|||.:.....|||::.|......
Mosquito   972 ICAQGPMDATINDFWRMIWEQHLEIIVMLTNLEEYNKTKCAKYWPESTNDSIQYGELLITFQSLT 1036

  Fly   236 QLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDED 300
            ..|::.|||.::.|.:........|.|.|:||..|.....|      |..:.:...:..|..:..
Mosquito  1037 YYADYIIRTLKVTKRSASSGEETSREISQYHYLAWKDFMAP------EHPQGITKFINRINSEYS 1095

  Fly   301 DMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDT 365
            ..|||||||||.|.||:|.::::|..::..:||....:|..:..:|..|..||::::||.|:|..
Mosquito  1096 LQRGPILVHCSAGVGRTGTFVALDTLMQQLQEEGQVFIFNTICDMRYQRNFLVQSLKQYIFLYRA 1160

  Fly   366 LEEHIICGKTWFPVSELSDRLKA-KARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNR 429
            |.|....|.|......|:..::| |...:...:::..:.::.:: |.....|......|...:|:
Mosquito  1161 LAELAYFGDTEIDQKSLASTIEALKQPSSENVEISRLELQFQRL-KAFQEDTRKTTTMGSSEENK 1224

  Fly   430 EKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQ 494
            .|||...|:|.|..|..|....|.....|||:.|:|||.....:::|:.||:.|:.:||.::::|
Mosquito  1225 AKNRSESCIPYDKNRVILAPIPGRDNCTYINASFIDGYDDENNFVITQDPMEDTIFDFWRMIFEQ 1289

  Fly   495 ECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKS---YTNIKQWEFKINKKIVSL 556
            ....:|:..:......:.|.:|.::..  ||..:. |.|:.|:|   ||          |:..::
Mosquito  1290 RIKTIVMFSEIGDGPNKCPRYWADEEM--KYENLL-VSYIQSESGPYYT----------KREFTV 1341

  Fly   557 TEMMAGVKAPTRTVQLFQLTCWP-MGHKVPSSTNSLVYLMNMVEIWRN-KVDYGPVCVVSPDGRS 619
            |.....   .|..|..||...|| :..:||..|..::.::|..:...: :.|...:.|....|..
Mosquito  1342 TNCKTN---DTIHVTQFQYNGWPTVEGEVPEVTRGMIEIVNQAQKHSSQQQDIFTIAVHCSLGTD 1403

  Fly   620 RAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHY 673
            ::.::.|....:.|:.....||:...|:.:|..|..:::...:|::.:..::::
Mosquito  1404 KSSLFVAMCILVMQLKTEKRVDICTVVRKLRAQRSLMIQTYAQYEFLHRAIVNF 1457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	80/242 (33%)
		Y_phosphatase	428..671	CDD:459674	58/247 (23%)
Ptp69D	XP_061508307.1	None