Protein Alignment Ptp36E and ptpn18

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_031746899.1
• Gene: ptpn18 / 101730699
• XenbaseID: XB-GENE-5829021
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 501
• Identity: 121/501 - (24%)
• Similarity: 197/501 - (39%)
• Gaps: 117/501 - (23%)

  Fly   104 LEFQT------AAKVESN-TCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYV 161
            ||||.      |...||: |........||:||:....:|||..||.:..:...:.|||:|||::
 Frog    29 LEFQEIRAQAGAFHKESDFTTEVGGSPENLKKNRYKDILPYDQTRVPVTFLSEEEGSDYINASFI 93

  Fly   162 DSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWP-PNMEVHEQYG 225
            ........||.||||:..|:|.:||||||..:..|||..:..:..|..|.:||| .:.....|:|
 Frog    94 KGTDPGRGYIATQGPLPHTIQDFWRMVWQYQVKVIVMACREVEHGKRKCERYWPLDDATTPAQFG 158

  Fly   226 DIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFSNALLEFRRRVRL 290
            ...|:.: |:...|..: .:|..::..::|..|   |..|.|..|.....|.|.:.  |...::|
 Frog   159 PFTISKL-EKNRVNAEV-IYRKLRVTFREESRD---ISHFQYVAWPDRGIPDSYSC--FLEMIQL 216

  Fly   291 VVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEEC---FNVFGYLKKLRQSRKGL 352
            |.    :.:.:.|.|:.||||.|.||:||...::....|.:.:..   |::|..:.::|:.|...
 Frog   217 VP----QYQRESRVPLCVHCSAGCGRTGVICMVEYIQSLLQRQRVPADFSIFNAVLQMRRQRPSA 277

  Fly   353 VENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTI 417
            |:..|||:|:|..             |:|:.|:....:|.....|.:           ::|.:
 Frog   278 VQTQEQYEFLYHA-------------VTEMFDKELQTSRCYENLKED-----------KSPLY-- 316

  Fly   418 GDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKH 482
             |.|....:..|:       :||...:|                       ..|..|..|:|
 Frog   317 -DDATSVLSALRQ-------LPPQRKKP-----------------------PARLPIGAEYP--- 347

  Fly   483 TLGEFWSLVYDQECSAVVVLCQPPSQSQQYPSFWPNK--SKMEKYGPVFSVHYVMSKSYTNIKQW 545
                              .||.|..:..|.|:...|:  :.::|..||.......:..|.|:.
 Frog   348 ------------------PLCAPEQRPGQMPAMSANETYAVVQKKRPVAPETRPQTVQYDNVP-- 392

  Fly   546 EFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSL 591
                       |.:...|..|....||:. |....|::. ||.|::
 Frog   393 -----------THVPTHVPTPAPLDQLYS-TVTHKGNRA-SSANAI 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	76/246 (31%)
		Y_phosphatase	428..671	CDD:459674	29/166 (17%)
ptpn18	XP_031746899.1	PTP_DSP_cys	30..295	CDD:475123	85/288 (30%)