Protein Alignment Ptp36E and ptprg

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_031757104.1
• Gene: ptprg / 100488629
• XenbaseID: XB-GENE-991516
• Length: 1411
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 200/715 - (27%)
• Similarity: 330/715 - (46%)
• Gaps: 81/715 - (11%)

  Fly    17 TGKHRSRS----------SARYDDV--EKQQRKSRA---------------IVSIPNTIKLSMLN 54
            |..|||||          ..|:..|  :.|...|.|               :||....:.|.:|.
 Frog   688 TTMHRSRSKEYSEGDTEVDIRFFTVNPDPQINSSMAMWPHPGKMEWIIPLVVVSALTFVCLILLL 752

  Fly    55 SGLLSFERIKLEAR--DENNSLSKTIPNGPIDI------------RHFLK-LCDLRRKFPVLYKL 104
            :.|:.:.:....|.  .|::|..:.|||..|.|            :.|:| :.:|.......:..
 Frog   753 AVLVYWRKCFQTAHFYVEDSSSPRVIPNESIPIIPIPDDMEAIPVKQFIKHISELYSNNQHGFSE 817

  Fly   105 EFQTAAKVESN---TCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGG--LQDSDYVNASYVDSL 164
            ||:...:..|:   |..|:...:|..||:....:.||::||.|..:.|  .:.|||:||:|||..
 Frog   818 EFEEVQRCTSDMNITAEHSNHPDNKHKNRYINIVAYDHSRVKLRPLPGKDSKHSDYINANYVDGY 882

  Fly   165 LKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFI 229
            .|..|||.||||::.|.:.:|||:|::|...|||:|...:..:..|.||||  .|..::||:|.:
 Frog   883 NKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWP--TENSDEYGNIMV 945

  Fly   230 NIVREEQLANFHIR--TFRLYKMNEKQEVT-----DERLILQFHYTEWYSHSCP-FSNALLEFRR 286
            .:......|.:.:|  |.|..||.:.|:..     :||.::|:|||:|.....| ::..:|.|.|
 Frog   946 TLKSTRVYACYTVRKFTIRNMKMKKGQKGNAKGRHNERTVMQYHYTQWPDMGVPEYALPVLTFVR 1010

  Fly   287 RVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKG 351
            |...|       :....||:|||||.|.||:|.|:.||:.|:..:::...|..|:||.:|..|..
 Frog  1011 RSSAV-------QLPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNALGFLKHIRTQRNY 1068

  Fly   352 LVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFT 416
            ||:..|||.||:|.|.|.|:..:|....::|...:.:......|.: ...:.::..:.:...::.
 Frog  1069 LVQTEEQYIFIHDALLEAILGKETEVCANQLHSYVNSILTPGPGGR-TRLEKQFRLVTQCNAKYV 1132

  Fly   417 IGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMK 481
              :|....:..|:||||:...||.:..|..|....|...|||||:.::.||.:..|:|:|:.||.
 Frog  1133 --ECFSAQKDSNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYLRSNEFIITQHPMP 1195

  Fly   482 HTLGEFWSLVYDQECSAVVVLCQPPSQSQQYPSF--WPNKSKMEKYGPVFSVHYVMSKSYTNIKQ 544
            ||..:||.:::|.....:|:|  |.:||.....|  ||::.:.... ..|:|..:.........:
 Frog  1196 HTTKDFWRMIWDHNAQIIVML--PDNQSLAEDEFVYWPSREESMNC-EAFTVTLISKDRLCLSNE 1257

  Fly   545 WEFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGP 609
            .:..|:..|:..|:     ......|:.||...||......||...|:.::....:.|:    ||
 Frog  1258 EQIIIHDFILEATQ-----DDYVLEVRHFQCPKWPNPDAPISSAFELINVIKEEALTRD----GP 1313

  Fly   610 VCVVSPDGRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674
            ..|....|...||..||.....:|:.....|||:|..|.:...||.:..::..|::.|..:|..:
 Frog  1314 TIVHDEFGAVSAGTLCALATLSQQMENENAVDVYQVAKMINLMRPGVFTDIEHYQFLYKAMLSLI 1378

  Fly   675  674
             Frog  1379  1378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	94/252 (37%)
		Y_phosphatase	428..671	CDD:459674	67/244 (27%)
ptprg	XP_031757104.1	alpha_CARP_receptor_like	67..319	CDD:239396
		FN3	349..426	CDD:214495
		R-PTPc-G-1	815..1088	CDD:350505	100/281 (36%)
		R-PTP-G-2	1172..1376	CDD:350508	55/215 (26%)