Protein Alignment Ptp36E and ptprdb

DIOPT Version :10

• Sequence 1: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_021330819.2
• Gene: ptprdb / 100073332
• ZFINID: ZDB-GENE-070615-38
• Length: 1952
• Species: Danio rerio
• Alignment Length: 725
• Identity: 206/725 - (28%)
• Similarity: 339/725 - (46%)
• Gaps: 131/725 - (18%)

  Fly    28 YDDVEKQQRKSR------------AIVSIPNTIKLSMLNSGLLSFERIKLEAR-----DENNSLS 75
            :.|||.|.....            |::.|.:.:.|.:|.......:|.:||.|     ....::|
Zfish  1279 FSDVEPQPIVDEEEGLLWVVGPVLAVIFIISIVILILLFKSKPDRKRAELEGRKCSFLSSGKAMS 1343

  Fly    76 KTIPNGPIDIRHFLKLCDLRRKFP---------------------------VLYKLEFQTAAKVE 113
            ...|:.|:::|        |..||                           :.:..|:::....:
Zfish  1344 SQHPSDPVELR--------RINFPTAGMTSHPPVSVSELPAHIERMKANDSLRFSQEYESIDPGQ 1400

  Fly   114 SNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNAYIVTQGPVE 178
            ..:..|:..:.|..||:....|.||:.||.|....|:...||:||:::|...:..|||.||||:.
Zfish  1401 QFSWEHSNLEINKPKNRYANVIAYDHTRVALTNTDGVAGGDYINANFIDGYRRQGAYIATQGPMP 1465

  Fly   179 ETVQAYWRMVWQENISAIVMLTK--------TFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREE 235
            :|...:|||||:::.:.::|:||        ::.|:|..|.||||....  |.||.:.::::...
Zfish  1466 DTFSDFWRMVWEQHTANVIMITKLEEKSRMPSYFFSKNKCDQYWPSRGT--ETYGLMQVSLLDTV 1528

  Fly   236 QLANFHIRTFRLYK--MNEKQEVTDERLILQFHYTEW-----YSHSCPFSNALLEFRRRVRLVVG 293
            :||.:.:|||.|:|  ..||:||.      ||.:|.|     ..|..||    |.|.|||:..
Zfish  1529 ELATYCVRTFALFKSGSGEKREVR------QFQFTAWPDQGVPEHPTPF----LAFLRRVKAC-- 1581

  Fly   294 NIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQ 358
                :..| .|||:||||.|.||:|.::.|||.||..::|:..:::|::..:|..|..:|:..||
Zfish  1582 ----NPPD-AGPIVVHCSAGVGRTGCFIVIDAMLERVKQEKTLDIYGHVTLMRSQRNYMVQTEEQ 1641

  Fly   359 YKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGG 423
            |.|||:.|.|.:.||.|..|    :..|.|..:|.|.|:..|:.:..:|..|:...      |..
Zfish  1642 YVFIYEALLEAVSCGNTEVP----ARNLYAYIQRLSQTEPPEHISGMEQEFKRLAN------AKA 1696

  Fly   424 HRAD--------NREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPM 480
            |.:.        |:.|||.|..:|.::.|..|...:|...:||:|..|:|||.:.|.||.|:.|:
Zfish  1697 HNSRFVSASLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYVNGSFIDGYRQQRAYIATQGPL 1761

  Fly   481 KHTLGEFWSLVYDQECSAVVVLCQPPSQS-QQYPSFWP-NKSKMEKYGPVFSVHYVMSKSYTNIK 543
            ..|:.:||.::::...:.||:|.:..... ::...:|| ::|...:|      ..|...:..|:.
Zfish  1762 AETVEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPSDRSARYQY------FVVDPMAEYNMP 1820

  Fly   544 QW---EFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKV 605
            |:   |||:       |:...|   .:|||:.||.|.|| ...||.|....:..:..|.  :.|.
Zfish  1821 QYILREFKV-------TDARDG---QSRTVRQFQFTDWP-EQGVPKSGEGFIDFIGQVH--KTKE 1872

  Fly   606 DY---GPVCVVSPDGRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCY 667
            .:   ||:.|....|..|.||:...:..:|::...|.||:||.||.:|..||.:|:...:|::||
Zfish  1873 QFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEEQYQFCY 1937

  Fly   668 DLVLHYVLHF 677
            ...|.|:..|
Zfish  1938 RAGLEYLGSF 1947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	93/257 (36%)
		Y_phosphatase	428..671	CDD:459674	74/250 (30%)
ptprdb	XP_021330819.2	None