DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42750 and dpep1

DIOPT Version :9

Sequence 1:	NP_724101.4	Gene:	CG42750 / 35090	FlyBaseID:	FBgn0261804	Length:	1068	Species:	Drosophila melanogaster
Sequence 2:	NP_001307047.1	Gene:	dpep1 / 768195	ZFINID:	ZDB-GENE-061013-388	Length:	414	Species:	Danio rerio

Alignment Length:	415	Identity:	183/415 - (44%)
Similarity:	267/415 - (64%)	Gaps:	33/415 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   662 WLAVSSILLIIGAASVAVPLALRVAASAPFEERLRVAVQLLDQVPLIDGHNDLPWNIRKFLHNKL 726
            |:.:..::|::            .:.|:..:|.:..|::|:|:.|||||||||||.:|...:|:|
Zfish     4 WVKILCLVLLV------------FSFSSEADELMDRALKLMDETPLIDGHNDLPWQMRDLFNNQL 56

  Fly   727 NDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQFWAAYVPCEAQHRDAVQLTLEQIDVIKRL 791
            ||.    ||.      |.:.:||::.:::.||:|||||||:|||:.|::|||:.||||||||.|:
Zfish    57 NDV----DLH------RLNSTHTNIEKIQHGRLSAQFWAAFVPCDTQYKDAVRQTLEQIDVIHRM 111

  Fly   792 TDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGHSLGGSLAVLRTLYAIGVRYMTLTSTCHTP 856
            .|:|........|:|||:||.:..:..||.|||||||:..||..|||:|.:||||:|||.:|:||
Zfish   112 CDKYPDDFKFAASSQDIMDAFEQNKTASLIGVEGGHSIDSSLGTLRTMYQLGVRYLTLTHSCNTP 176

  Fly   857 WADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMMVDLSHVSKGTMRDALEVSEAPVIFSHSSA 921
            |||:...|..:..:::.||:.|||.::.||||:||::||||||:..|...|::|:||:|||||||
Zfish   177 WADNWLMDTESNPVRNIGLSEFGKQVVWEMNRIGMLIDLSHVSEKVMNQVLDISKAPIIFSHSSA 241

  Fly   922 YELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSCSDNSTVHDAVAHINHIKRVAGIDHVGLGA 986
            |.:|...|||.||:|..:..|.|:|||||::.:::|::::|:.|...|.:|||:||....:|.|.
Zfish   242 YSICKHKRNVPDDVLVKVKTNRGIVMVNFFNDYVTCNEHATLSDVADHFDHIKKVADASIIGFGG 306

  Fly   987 GYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELTKLAGGNFLRVMQQVEKLRDDKKAAGVKPF 1051
            .|||:...|.||||||.||.|..|||..||:.:|:....|.|.|||.:.||.:||..:  ..||
Zfish   307 DYDGVPRVPVGLEDVSKYPDLVVELLRRGWSDNEIKDALGRNLLRVFRDVENVRDSLR--NTKP- 368

  Fly  1052 EDHP--------NFRTDDPYNCTSS 1068
            :|.|        ..|||..|:..||
Zfish   369 DDKPIPLKEVQNPCRTDYGYSDKSS 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:279569	164/333 (49%)
dpep1	NP_001307047.1	Peptidase_M19	31..355	CDD:279569	164/333 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	347	1.000	Domainoid score	I1002
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		otm26602
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X677
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.780