Protein Alignment CG42750 and DPEP3

DIOPT Version :10

• Sequence 1: NP_724101.4
• Gene: CG42750 / 35090
• FlyBaseID: FBgn0261804
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_001357127.1
• Gene: DPEP3 / 64180
• HGNCID: 23029
• Length: 488
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 188/436 - (43%)
• Similarity: 245/436 - (56%)
• Gaps: 45/436 - (10%)

  Fly   635 PWKHRQCPSRGSSSSGTNSFRFDAAKHWLAVSSILLIIGAASVAVP--LALRVAASAPFEERLRV 697
            |...|...:.||.|..|..          .|.|.|...|..:...|  |.||..|.|
Human    40 PGAPRALSTLGSPSLFTTP----------GVPSALTTPGLTTPGTPKTLDLRGRAQA-------- 86

  Fly   698 AVQLLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQ 762
               |:...||:|||||||..:|:...|.|.|.|    |||.     || ..|.|.||:.|.:.||
Human    87 ---LMRSFPLVDGHNDLPQVLRQRYKNVLQDVN----LRNF-----SH-GQTSLDRLRDGLVGAQ 138

  Fly   763 FWAAYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGH 827
            ||:|.|.|::|.:.||:|.|||||:|.|:...|| :|...|||:.:   :.:|:|..|.||||||
Human   139 FWSASVSCQSQDQTAVRLALEQIDLIHRMCASYS-ELELVTSAEGL---NSSQKLACLIGVEGGH 199

  Fly   828 SLGGSLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMM 892
            ||..||:|||:.|.:||||:|||.||.||||:||............|||.||:.::.|:||||||
Human   200 SLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMM 264

  Fly   893 VDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSC 957
            :|||:.|...:|..||||:||||||||:|..:|:...||.|||||.|.||||:|||......|.|
Human   265 IDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQC 329

  Fly   958 SDNSTVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELT 1022
            :..:.|.....|.:||:.|.|.:.:|:|..|||....|:||||||:||.|..|||...|:.:||.
Human   330 NLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQ 394

  Fly  1023 KLAGGNFLRVMQQVEKLRDDKKAAGVKPFEDHPNFRTDDPYNCTSS 1068
            .:..||.|||.:||||:|::.:|.  .|.|      .:.||...|:
Human   395 GVLRGNLLRVFRQVEKVREESRAQ--SPVE------AEFPYGQLST 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:395996	161/333 (48%)
DPEP3	NP_001357127.1	Peptidase_M19	87..407	CDD:395996	161/333 (48%)