DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42750 and Dpep3

DIOPT Version :9

Sequence 1:	NP_724101.4	Gene:	CG42750 / 35090	FlyBaseID:	FBgn0261804	Length:	1068	Species:	Drosophila melanogaster
Sequence 2:	NP_001008384.1	Gene:	Dpep3 / 364994	RGDID:	1305484	Length:	488	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	183/417 - (43%)
Similarity:	239/417 - (57%)	Gaps:	41/417 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   661 HWLAVSSILLIIGAASVAVPLALRVAASAP------------------------FEERLR-VAVQ 700
            |.|::..:||||.:..|.........:|||                        .:.||| .|:.
  Rat    19 HRLSLLGVLLIIPSLWVTCNQTTPSLSSAPTSPGASSAMTTPGIPNDTTTSGVTSDPRLREQALA 83

  Fly   701 LLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQFWA 765
            |:...||:|||||||..:|:...|||.|.|.....|          ..|.|.||:.|.:.||||:
  Rat    84 LMRDFPLVDGHNDLPLLLRELFQNKLQDVNLHNFTR----------GQTSLDRLRDGLVGAQFWS 138

  Fly   766 AYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGHSLG 830
            ||:||:.|.||||::.|||||:|:|:...| |:|...|||..:   :..|:|..|.|:||||||.
  Rat   139 AYIPCQTQDRDAVRVALEQIDLIRRMCSAY-PELELVTSADGL---NSTQKLACLIGLEGGHSLD 199

  Fly   831 GSLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMMVDL 895
            .||||||:.|.:||||:|||.||.||||:|:......|.....|||.||:.::.||||:|||:||
  Rat   200 TSLAVLRSFYELGVRYLTLTFTCSTPWAESATKFRHHFYTNISGLTSFGEKVVEEMNRIGMMIDL 264

  Fly   896 SHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSCSDN 960
            ||.|...::..||.|.||||||||:|..:|:...||.|||||.|.||||:|||......|.||..
  Rat   265 SHASDTLVKQTLEASRAPVIFSHSAARSVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCSLL 329

  Fly   961 STVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELTKLA 1025
            :.|.....|.:||:.|.|.:.:|:|..|||....|:||||||:||.|..|||..||...||..:.
  Rat   330 ANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLLEELLRRGWGEQELQGVL 394

  Fly  1026 GGNFLRVMQQVEKLRDDKKAAGVKPFE 1052
            .||.|||.:|||::|:  |:.|..|.|
  Rat   395 RGNLLRVFRQVEQVRE--KSLGQSPVE 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:279569	161/333 (48%)
Dpep3	NP_001008384.1	Podoplanin	26..>76	CDD:283467	8/49 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	41..74		3/32 (9%)
		Peptidase_M19	83..404	CDD:279569	161/334 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	330	1.000	Domainoid score	I1118
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X677
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.780