Protein Alignment CG42750 and Dpep2

DIOPT Version :10

• Sequence 1: NP_724101.4
• Gene: CG42750 / 35090
• FlyBaseID: FBgn0261804
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: XP_006531144.1
• Gene: Dpep2 / 319446
• MGIID: 2442042
• Length: 611
• Species: Mus musculus
• Alignment Length: 677
• Identity: 242/677 - (35%)
• Similarity: 321/677 - (47%)
• Gaps: 138/677 - (20%)

  Fly   386 DEIFSPHSKKSDP--SLCFLPGGNTSSKYNTIGPSSDYARHLAHYSRYLQKQHHQQQMAHFQQQR 448
            |.||..:|..|..  ..|:      |:......|||      ..|...|.|.|.|.|||...:..
Mouse     3 DRIFYINSNLSSVPCEACY------STPMPPTAPSS------PGYYHVLYKGHAQAQMAWHGETY 55

  Fly   449 C-----RCFSQSLLSFPQQQQQQQQQQQHQQMQHAEQQQQHKAAQQPAIFHTSSMDWSLPINSRS 508
            |     |.:..:.|..|.:.:|:            |:....:|.::..:...|..|...|
Mouse    56 CLIGGYRVYGDAPLPTPAKAEQE------------EKPVPRRAPKRQRVQEESDQDLGCP----- 103

  Fly   509 FGNLVNIDGSGGTGGCRVPYQKMQSGNAGSGGAMANGCLGLAASSTFTLTSFDSD--IGHGLKER 571
                          |.:||..|::.|  |.|.:..:.....:|.|..:||.....  :||||...
Mouse   104 --------------GAKVPRLKLKHG--GKGLSRPSSVPACSALSKMSLTGLKGHWVLGHGLSVF 152

  Fly   572 ESQTSLHHPHTLPHPHPHTHSHSHPHHYHAHVGGAAVSGGVGGSGSVTPQKHHQLHSSVTSIMPW 636
            .....|..|     ..|...:.:.|                |.||           :|.||.:|
Mouse   153 LLVLLLLGP-----SQPLIWTQTKP----------------GFSG-----------ASTTSSIP- 184

  Fly   637 KHRQCPSRGSSSSGTNSFRFDAAKHWLAVSSILLIIGAASVAVPLALRVAASAPFEERLRVAVQL 701
                   |..:...              :|||....|..:.           ....:|.|.   |
Mouse   185 -------RALTKPD--------------ISSIPTTPGNPNF-----------PDLRDRARA---L 214

  Fly   702 LDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQFWAA 766
            :.:.||||||||:|..:|:|..|.|.|.|    |||.     :| ..|.|.|||.|.:.||||:|
Mouse   215 MQEFPLIDGHNDMPLVLRQFYQNGLQDAN----LRNF-----TH-GQTSLDRLKDGLVGAQFWSA 269

  Fly   767 YVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGHSLGG 831
            ||||:.|.|||::|||||||:|:|:...|| :|...||.:.:   :..|:|..|.||||||||..
Mouse   270 YVPCQTQDRDALRLTLEQIDLIRRICASYS-ELELVTSVKAL---NSTQKLACLIGVEGGHSLDN 330

  Fly   832 SLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMMVDLS 896
            ||||||:.|.:||||:|||.||:||||::|......|.....|||.||:.::.||||||||||||
Mouse   331 SLAVLRSFYLLGVRYLTLTHTCNTPWAETSSKGVHAFYSSVTGLTSFGEKVVAEMNRLGMMVDLS 395

  Fly   897 HVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSCSDNS 961
            |||....|.|||||:||||||||:|..:|..:||:.||:||.|.||||:|||.|....|.|:..:
Mouse   396 HVSDAAARRALEVSQAPVIFSHSAARAVCPNARNLPDDLLQLLKKNGGIVMVTFSVGVLPCNPLA 460

  Fly   962 TVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELTKLAG 1026
            .|.....|.:||:.|.|.:.:|:|..|||....|:||||||:||.|..|||..||...||..:..
Mouse   461 NVSTVADHFDHIRSVIGSEFIGIGGDYDGTKQFPQGLEDVSTYPVLIEELLRRGWNEQELQGILR 525

  Fly  1027 GNFLRVMQQVEKLRDDKKAAGVKPFED 1053
            ||.|||.:|||::||  |:....|.||
Mouse   526 GNLLRVFRQVEQVRD--KSKWQSPLED 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:395996	172/333 (52%)
Dpep2	XP_006531144.1	Peptidase_M19	214..534	CDD:395996	172/333 (52%)