Protein Alignment CG42750 and DPEP1

DIOPT Version :10

• Sequence 1: NP_724101.4
• Gene: CG42750 / 35090
• FlyBaseID: FBgn0261804
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_004404.1
• Gene: DPEP1 / 1800
• HGNCID: 3002
• Length: 411
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 152/353 - (43%)
• Similarity: 224/353 - (63%)
• Gaps: 8/353 - (2%)

  Fly   698 AVQLLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQ 762
            |.:::...|:|||||||||.:....:|:|.|     :..|:....   .:||::.:|:.|.:..|
Human    23 AERIMRDSPVIDGHNDLPWQLLDMFNNRLQD-----ERANLTTLA---GTHTNIPKLRAGFVGGQ 79

  Fly   763 FWAAYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGH 827
            ||:.|.||:.|::|||:.||||:||:.|:...|.......||:..|..|.:..::.||.||||||
Human    80 FWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGH 144

  Fly   828 SLGGSLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMM 892
            |:..||.|||.||.:|:||:|||.:|:|||||:...|......:..||:.||:.:::|:||||::
Human   145 SIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVL 209

  Fly   893 VDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSC 957
            :||:|||..||:..|::|.|||||||||||.:|.:.|||.||:|:.:.:...|||||||:.::||
Human   210 IDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISC 274

  Fly   958 SDNSTVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELT 1022
            ::.:.:.....|::|||.|||...||.|..:||:...|:||||||.||.|.||||...||..|:.
Human   275 TNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVK 339

  Fly  1023 KLAGGNFLRVMQQVEKLRDDKKAAGVKP 1050
            .....|.|||.:.||:..:..:|...:|
Human   340 GALADNLLRVFEAVEQASNLTQAPEEEP 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:395996	147/333 (44%)
DPEP1	NP_004404.1	Peptidase_M19	26..352	CDD:395996	147/333 (44%)