DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42750 and CETN1

DIOPT Version :9

Sequence 1:	NP_724101.4	Gene:	CG42750 / 35090	FlyBaseID:	FBgn0261804	Length:	1068	Species:	Drosophila melanogaster
Sequence 2:	NP_004057.1	Gene:	CETN1 / 1068	HGNCID:	1866	Length:	172	Species:	Homo sapiens

Alignment Length:	156	Identity:	31/156 - (19%)
Similarity:	53/156 - (33%)	Gaps:	60/156 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   885 EMNRLGMMVDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVN 949
            ||.::...||.....|.:..|.|.|....:            :.::.:::||:|
Human    68 EMKKMISEVDREGTGKISFNDFLAVMTQKM------------SEKDTKEEILKA----------- 109

  Fly   950 FYSKFLSCSDNSTVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGG 1014
                |....|:.|   ......::||||.    .||.     |.|.:.|:::
Human   110 ----FRLFDDDET---GKISFKNLKRVAN----ELGE-----NLTDEELQEM------------- 145

  Fly  1015 GWTIDELTKLAGG-----NFLRVMQQ 1035
               |||..:...|     .|||:|::
Human   146 ---IDEADRDGDGEVNEEEFLRIMKK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:279569	31/154 (20%)
CETN1	NP_004057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
CETN1	NP_004057.1	PTZ00183	22..172	CDD:185503	31/156 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900