Protein Alignment Socs36E and socs4

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_021322920.1
• Gene: socs4 / 797891
• ZFINID: ZDB-GENE-070720-4
• Length: 423
• Species: Danio rerio
• Alignment Length: 496
• Identity: 151/496 - (30%)
• Similarity: 217/496 - (43%)
• Gaps: 135/496 - (27%)

  Fly   168 SVGAAISTLQLHDNHGGNANCPLEADDDDDLDESLL--------RRRRSNSNSRSNIHHHHHHHQ 224
            ||.|.:|   ||...... :.||..::.|.|.|:|.        .|:..||::|.
Zfish     6 SVDAELS---LHKLQAWK-HSPLFCENIDFLSEALFGKGPEAMSERKTKNSDTRP---------- 56

  Fly   225 QQQQQQHEAEVVEYCEVLESLPVSNMLSAGTQHSSKPVSRSNNSNSCCRSRSSKALSMGAATSSA 289
                                   .|:.|.......:.:.:        |||.|:..:........
Zfish    57 -----------------------KNLRSWSADSYIRSIKK--------RSRGSRHETAPRGEEGD 90

  Fly   290 SGSASTSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSSSSSVSNKKDAAAVVAMVPRKSRTADRRS 354
            .....|:.|.|...:||...|.|         .:|..:.|.|..:.|.:
Zfish    91 GADEQTARSASCPRRRRERMCSC---------TIPGETDSDSPCRKALS---------------- 130

  Fly   355 TPPTLGTSSGGSQRRMQSQRIRNSV--AVPDASHHHHQLIIRITSPGFVVESPNGGRVTV---VT 414
                         ||...|:.:::|  .:|..:||||......:|..|.|...:..::.|   :.
Zfish   131 -------------RRSLRQKFQDAVGQCLPLRNHHHHHHHPSGSSRPFSVLLWSKRKIHVSELME 182

  Fly   415 EPAPQSP------------------------QTPPRPRPLATVAPA-------GGAGHAGIG--- 445
            :..|.||                        :|.|:...|::..|.       |..|.:.:.
Zfish   183 DKCPFSPKSELAQCWHLIKKHGTNTKPSLSIETEPKGPLLSSTPPTLLSWEQIGSTGASSLDDWD 247

  Fly   446 ---AARNMTVHSQIDFMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFL 507
               |..:....:..|::  |||||.:|.||..|||.:||:|||.||||:||||||||||||:|:|
Zfish   248 PSFALGDSQCCAHTDYI--LVPDLLQINNSPCYWGVLDRFEAEQLLEGQPEGTFLLRDSAQDEYL 310

  Fly   508 FSVTFRKYGRSLHARIEQSGHKFSFDCHDPCVFTAPTVTGLLEHYKDPACVMFFEPCLTIPLHRR 572
            |||:||:|.|||||||||:|.:||||..|||::...:|||||:||.||:..:||||.|:.||.|.
Zfish   311 FSVSFRRYSRSLHARIEQNGKRFSFDGRDPCMYRDSSVTGLLKHYSDPSTCLFFEPLLSRPLPRN 375

  Fly   573 QTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYK 613
            ..||||.|.||.|.|.|:|.||..:.||..|:.:|::|||:
Zfish   376 FPFSLQHLCRAVICSCTTYQGIEALPLPYTLRHFLRQYHYR 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	67/99 (68%)
		SOCS	575..626	CDD:470605	20/39 (51%)
socs4	XP_021322920.1	SOCS	100..150	CDD:432667	14/87 (16%)
		SH2	266..366	CDD:472789	67/99 (68%)
		SOCS	376..>416	CDD:470605	19/39 (49%)