Protein Alignment Socs36E and socs5a

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001107230.1
• Gene: socs5a / 768142
• ZFINID: ZDB-GENE-061013-408
• Length: 528
• Species: Danio rerio
• Alignment Length: 582
• Identity: 192/582 - (32%)
• Similarity: 255/582 - (43%)
• Gaps: 137/582 - (23%)

  Fly    93 VEQEEEQQRQ----C--ADGATDDDAAALSADSLNANGQIVNVTLEGGYGEVGVVTNRTAGSSPE 151
            ||...:.|.|    |  .|||..|       .:|:||....:|      ..:.:|..||:||
Zfish    27 VETSPQHQPQTDTVCHSVDGAQGD-------ITLDANSPSSSV------AALPLVAWRTSGS--- 75

  Fly   152 AAKTERQPVNNNGLAGSVGAAISTLQLHDNHGGNANCP--LEADDDDDLDES---LLRRRRSNSN 211
                    |...|                 |...|:.|  ||...:.|.|::   |..||.|.|
Zfish    76 --------VTRRG-----------------HNCVADVPQILEITVEQDADDARAPLGARRDSYS- 114

  Fly   212 SRSNIHHHHHHHQQQQQQQHEAEVVEYCEVLESLPVSNMLSAGTQHSSKPVSRSNNSNSCCRSRS 276
                     .|.....:::|..          |....:.|....:.|.:...|...|||.....|
Zfish   115 ---------RHAPWSGKKRHSC----------STKAQSSLETTDRRSGRSRRRHGTSNSPEELES 160

  Fly   277 SKALSMGAATSSASGSA----STSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSSSSSVSNK---- 333
            ....|:........|..    |:|.:|.....:|  |.:..:.:.......|  .|.::.|
Zfish   161 GTTRSIRQQIHDTVGLCLPLRSSSRNTHLPPPKR--KIQITELMLETCPFAP--GSDLARKWHLI 221

  Fly   334 KDAAAVVAMVPRKSRTADRRSTPPTLGTSSGGSQRRMQSQRIRNSVAV-------PDASHHHHQL 391
            |...|.:.::|..       |:|...|.:....:...:..|.|..:::       |||..|   .
Zfish   222 KQHTAPINVIPLD-------SSPDACGATCASPEDEEERLRERRRLSIEEGVDPPPDAQIH---T 276

  Fly   392 IIRITSP---------------GFVVESPNGG----------RVTVVTEPAPQSPQTPPRPRPLA 431
            :..||:|               |..|....|.          ..|.:...|.:..|.
Zfish   277 VEAITAPLASLYKLGPKLAPGMGEAVGDSRGAAAANCDSEDDETTTLCLQARKPKQW-------- 333

  Fly   432 TVAPAGGAGHAGIGAARNMTVHSQIDFMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTF 496
               .|.|.||..........||:|||::|||||||.:||....|||.|||||||.||:|:|||||
Zfish   334 ---QASGEGHPSSKQPGPWKVHTQIDYIHCLVPDLLQITALPCYWGVMDRYEAEALLDGRPEGTF 395

  Fly   497 LLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCHDPCVFTAPTVTGLLEHYKDPACVMFF 561
            ||||||||::||||:||:|||||||||||..|.||||.||||||.|.|||.||||||||:..|||
Zfish   396 LLRDSAQEDYLFSVSFRRYGRSLHARIEQWNHNFSFDAHDPCVFHAATVTALLEHYKDPSACMFF 460

  Fly   562 EPCLTIPLHRRQTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYKQKLRVKPIDQ 623
            ||.||:||||...|.||.|:||.|....:||||..:.||..|:.||:||||||::||:.:::
Zfish   461 EPLLTVPLHRTFPFGLQSLARAAICHGITYDGIGALPLPPALQDYLREYHYKQRVRVRWLER 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	75/99 (76%)
		SOCS	575..626	CDD:470605	24/49 (49%)
socs5a	NP_001107230.1	SOCS	123..186	CDD:432667	13/72 (18%)
		SH2	362..462	CDD:472789	75/99 (76%)
		SOCS	471..526	CDD:470605	24/52 (46%)