Protein Alignment Socs36E and cish

DIOPT Version :9

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001070085.1
• Gene: cish / 767678
• ZFINID: ZDB-GENE-050907-1
• Length: 212
• Species: Danio rerio
• Alignment Length: 231
• Identity: 60/231 - (25%)
• Similarity: 99/231 - (42%)
• Gaps: 48/231 - (20%)

  Fly   410 VTVVTEPAPQS--PQTPPR--PRPLATVAPAGGAGHAGIGAARNMTVHSQIDFMHCLVPDLEKIT 470
            :..|..|:|::  |.:.||  ..|..|:..|..                  |: ..|..:...:.
Zfish     2 ILCVEGPSPRALLPFSSPRRIDEPFLTIEDASK------------------DY-RALTLNFSYLD 47

  Fly   471 NSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCH 535
            .|.:|||.:...||..:|:|..|||||:|||:..:::.:::.:......:.|||....:||.|..
Zfish    48 ASGWYWGGISASEAHSVLKGASEGTFLIRDSSHPDYMLTLSVKTVRGPTNVRIEYRQCRFSLDSS 112

  Fly   536 DPC---VFTAPTVTGLLEHY------------KDPACVMFFEP--C-----LTIPLHRRQTF-SL 577
            .|.   :.:.|.|..|::||            ::...|:...|  |     |..|:|..|.| ||
Zfish   113 SPARSHLQSFPDVHSLVQHYVGSKSEKNEEKMEEAHHVISSAPKECSVLLKLKKPIHCPQGFPSL 177

  Fly   578 QQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYK 613
            :.|:|..|..:||  ....:.||..|..||:.|.::
Zfish   178 KHLTRLVINKHTS--STEMLPLPNPLLYYLQNYPFQ 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589	29/114 (25%)
		SOCS	575..626	CDD:295349	14/40 (35%)
cish	NP_001070085.1	SH2_CIS	46..133	CDD:198285	27/86 (31%)
		SOCS	175..212	CDD:295349	13/39 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575801
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740