Protein Alignment Socs36E and socs5b

DIOPT Version :9

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_005156658.1
• Gene: socs5b / 559639
• ZFINID: ZDB-GENE-080722-18
• Length: 598
• Species: Danio rerio
• Alignment Length: 631
• Identity: 191/631 - (30%)
• Similarity: 281/631 - (44%)
• Gaps: 141/631 - (22%)

  Fly    38 LDEEELQVEEILTEATVSAATSPAEVRQIIIKIQLAKMENGNPVAAG---------QVESFAEV- 92
            |..::|.....:.:....|...|.|.|.......|:.:    |:|.|         .:....|:
Zfish    63 LCSQDLDCAHCVLDLDRGAHAEPYETRSSTPSRNLSPL----PLATGGRRSHNCVADIPQIVEIS 123

  Fly    93 VEQEEEQQRQCA-------------DGATDDDAAALSADSLNANGQIVNVTLEGGYGEVGVVTNR 144
            :::|.|..|:..             .|......:..:..||.|:.:                |.|
Zfish   124 IDKESEDARRGPLVRRDSYSRHAPWGGKKKHSCSTKTQSSLEADRR----------------TGR 172

  Fly   145 TAGSSPEAAKTER-------QPVNNNGLAGSVGAAISTLQLHDNHGGNANCPLEADDDDDLDESL 202
            :.||:   |:.||       |.:|::...||.|.::|:..|..          ...|...|...|
Zfish   173 SRGST---ARRERRYAVSSIQEINDSVEVGSSGRSLSSRSLRQ----------RLRDTVGLCLPL 224

  Fly   203 LRRRRSNSNSRSNIHHHHHHHQQQQQQQHEAE-VVEYCEVLESLPVSNMLSAGTQHSSKPVSRSN 266
            ...|||.| ::..:        ..:::.|..| ::|.|.......::|......||:: |||..:
Zfish   225 PTHRRSQS-AKGQV--------SSKRKIHLTELMLETCPFPPGSDLANKWHLIKQHTA-PVSPHS 279

  Fly   267 NSNSCCRSRSSKALSMGAATSSASGSASTSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSS---SS 328
            :|                |...|..||.:|........|...:....:.:    |..|::   :.
Zfish   280 SS----------------ALFDAFDSAHSSPEDEEERLRERRRLSIEEGV----DPPPNAQIHTL 324

  Fly   329 SVSNKKDAAAVVA--MVPRKSRTADRRSTPPTLGTSSGGSQRRMQSQRIRNSVAVP------DAS 385
            ..::|..:...:.  |.|....|.....:..|:.:.|||...  .:.::..|:|||      |:.
Zfish   325 EATSKSSSLYKLGPKMAPGVGETLGEGRSLGTVSSISGGLSG--IAAQVPTSMAVPSHTVDCDSE 387

  Fly   386 HHHHQLIIRITSPGFVVESPNGGRVTVVTEPAPQSPQTPPRPRPLATVAPAGGAGHAGIGAARNM 450
            .....|.::...|   .:....|......:|.|                               .
Zfish   388 EDSTTLCLQTRRP---KQRHASGDTHCSRQPGP-------------------------------W 418

  Fly   451 TVHSQIDFMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKY 515
            .||:|||::|||||||:.||....|||.||||:||.||:|:|||||||||||||::||||:||:|
Zfish   419 KVHTQIDYIHCLVPDLQAITALPCYWGVMDRYQAEALLDGRPEGTFLLRDSAQEDYLFSVSFRRY 483

  Fly   516 GRSLHARIEQSGHKFSFDCHDPCVFTAPTVTGLLEHYKDPACVMFFEPCLTIPLHRRQTFSLQQL 580
            .|||||||||..|.||||.||||||.:.||||||||||||:..|||||.||.||||...||||.|
Zfish   484 NRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSACMFFEPLLTAPLHRTFPFSLQHL 548

  Fly   581 SRATIVSNTSYDGINQMELPGRLKSYLKEYHYKQKLRVKPIDQNTP 626
            :|::|..:|:||||..:.||..::.:|||||||||:||:.:::..|
Zfish   549 ARSSICRHTTYDGIGALPLPPTMQDFLKEYHYKQKVRVRWLEREPP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589	73/99 (74%)
		SOCS	575..626	CDD:295349	25/50 (50%)
socs5b	XP_005156658.1	SOCS	174..228	CDD:289383	15/66 (23%)
		SH2	431..531	CDD:301589	73/99 (74%)
		SOCS_SOCS5	540..596	CDD:239708	26/55 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575793
Domainoid	1	1.000	99	1.000	Domainoid score	I7025
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002657
OrthoInspector	1	1.000	-	-		otm24619
orthoMCL	1	0.900	-	-		OOG6_109258
Panther	1	1.100	-	-	LDO	PTHR10155
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2417
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.740