Protein Alignment Socs36E and socs6b

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_955919.1
• Gene: socs6b / 322950
• ZFINID: ZDB-GENE-030131-1670
• Length: 532
• Species: Danio rerio
• Alignment Length: 589
• Identity: 139/589 - (23%)
• Similarity: 208/589 - (35%)
• Gaps: 171/589 - (29%)

  Fly   110 DDAAALSADSLNANGQIVNVTLEGGYGEVGVVTNRTAGSSPEAAKTERQPVNNNGLAGSVGAAIS 174
            |.||:.||:.          :|.||.....:|::.......:.:|...:   :.||.|::...:|
Zfish    29 DLAASFSAED----------SLFGGCYSKDLVSSDLDNEDEKRSKVRSK---SEGLMGTLKRRLS 80

  Fly   175 TLQLHDNHGGNAN-CPLEADDDDDLDES----LLRRRRSNSNSRSNIHHHHHHHQQQQQQQHEAE 234
            ..|.....||:.: |.:   |||....|    .|...:|..:|||...|.||:
Zfish    81 AKQKPKVKGGSPSVCSI---DDDTFSSSSAPISLSDLKSQRSSRSTSVHSHHY------------ 130

  Fly   235 VVEYCEVLESLPVSNMLSAGTQHSSKPVSRSNNSNSCCRSRSSKALSMGAATSSA---------- 289
                              :.|....:||    ||...|.....|||...:..||.
Zfish   131 ------------------SPTPWPLRPV----NSEETCIKMDVKALMNSSDPSSTLNSVHQDFLD 173

  Fly   290 ----SGSASTSVSTSTSSKRRCCKCKCRD----------AIRGLR-------------DMLPSSS 327
                .|.:|.|...:|.........:..|          .:.||.             .:.|...
Zfish   174 LQREFGESSDSFRITTRVPDHHSATQNGDLHLDMDEHVPVVLGLAAQDYIQYTMPLDDGLYPDDE 238

  Fly   328 SSVSNKKDAAAVVAMVPRKSRTADRRSTPPTLGTSSGGSQRRMQSQRIRNSVAVPD---ASHHHH 389
            .|.|...||...:.:||:                |.|........:.|...:..||   .|...:
Zfish   239 GSRSFCLDATTPMDIVPQ----------------SEGCGSLHQDEEPIDQDLLSPDIFMESSSVN 287

  Fly   390 QLIIRITSPGFVVESPNGGRVTVVTEPAPQSPQTPPRPRPLATVAPAGGAG-HAGIGAARNMTVH 453
            ||.:...:...     .|.|:     .||.||..||.|......:.:|.|| ||.:  |..:..|
Zfish   288 QLFLNTANVLL-----QGSRL-----EAPLSPLLPPLPDSYLQRSFSGFAGTHAQV--AERVMHH 340

  Fly   454 SQID--------------------FMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLL 498
            ...|                    .:..|..:|:|:....:|||.:.|:|||..|...|:|:||:
Zfish   341 LNFDPNSAPGVQRVYDAVQNSGPMVVTSLTAELKKLAKQGWYWGPITRWEAEEKLTNLPDGSFLV 405

  Fly   499 RDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCHDPCVFTAPTVTG------LLEH-YKDPA 556
            |||:.:.:|.|::||...::||.|||.|...|||       :..|.:.|      |::: .||..
Zfish   406 RDSSDDRYLLSLSFRSQTKTLHTRIEHSNGSFSF-------YEQPDIEGHVSIVDLIDNSVKDSE 463

  Fly   557 CVMF------------FEPCLTIPLHR-RQTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLK 608
            ...|            :...||.|:.| .|..|||.|.|..|...|..|.|.::.||.::|.||:
Zfish   464 NGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQ 528

  Fly   609 EYHY 612
            |.||
Zfish   529 EKHY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	36/118 (31%)
		SOCS	575..626	CDD:470605	17/38 (45%)
socs6b	NP_955919.1	SH2_SOCS6	370..469	CDD:198250	36/105 (34%)
		SOCS_SOCS6	492..532	CDD:239709	16/39 (41%)