Protein Alignment Socs36E and Socs4

DIOPT Version :9

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001100726.1
• Gene: Socs4 / 305828
• RGDID: 1306503
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 431
• Identity: 161/431 - (37%)
• Similarity: 209/431 - (48%)
• Gaps: 87/431 - (20%)

  Fly   258 SSKPVSRSNNSNSCCRSRSSKAL--------SMGAATSSASGSASTSVSTSTSSKRRCCKCKCRD 314
            |.|.:|.|..|.||..|.:...|        |.....|.:|.......|.......|..|.|.:|
  Rat    30 SGKKLSWSRKSESCSESEAVGTLESVEIPLRSQERELSCSSIELDLDHSCGHRFLGRSLKQKLQD 94

  Fly   315 AIR---GLRDMLPSSSSSVSNKKDAAAVVAMVPRKSRTADRRSTPP--------------TLGTS 362
            |:.   .:|:.....|..:.:|:.......|:       |:...||              |:..|
  Rat    95 AVGQCFPIRNCGARHSPGLPSKRTIHISELML-------DKCPFPPPSDLAFRWHFIKRHTVALS 152

  Fly   363 SGGSQ-----------RRMQSQRIRNSVAVPDASHHHHQLIIRITSPGFVVESPNGGRVT----- 411
            |...:           |..|.:|......:|..||...|..:..|:..    |..||.||
  Rat   153 SSSDEWVSTDLCERRPRDAQLKRRSTEDDIPCFSHTSVQPCVITTNSA----SCAGGHVTGSLMN 213

  Fly   412 VVTEPAPQ---------------SPQTPPRPR------PLATVAPAGGAGHAGIGAARNMTVHSQ 455
            :||:.:.:               |.:...:||      .|...||.              ..|:|
  Rat   214 LVTDNSMEDGDMDSEDEIITLCTSSRKRNKPRWETDDGILQLEAPP--------------KFHTQ 264

  Fly   456 IDFMHCLVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLH 520
            ||::|||||||.:|:|:..|||.||:|.||.||||||||||||||||||::||||:||:|.||||
  Rat   265 IDYVHCLVPDLLQISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLH 329

  Fly   521 ARIEQSGHKFSFDCHDPCVFTAPTVTGLLEHYKDPACVMFFEPCLTIPLHRRQTFSLQQLSRATI 585
            |||||..|.||||.||||||.:|.:||||||||||:..|||||.|:.||.|...||||.:.|..|
  Rat   330 ARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVI 394

  Fly   586 VSNTSYDGINQMELPGRLKSYLKEYHYKQKLRVKPIDQNTP 626
            .:.|:||||:.:.:|..:|.||||||||.|:|:..||...|
  Rat   395 CNCTTYDGIDALPIPSPMKLYLKEYHYKSKVRLLRIDVPEP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589	73/99 (74%)
		SOCS	575..626	CDD:295349	25/50 (50%)
Socs4	NP_001100726.1	SOCS	58..105	CDD:289383	10/46 (22%)
		SH2_SOCS4	272..372	CDD:198248	73/99 (74%)
		SOCS	381..436	CDD:295349	26/55 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336661
Domainoid	1	1.000	97	1.000	Domainoid score	I7083
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002657
OrthoInspector	1	1.000	-	-		otm46119
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10155
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2417
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.800