Protein Alignment Socs36E and Socs1

DIOPT Version :9

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_665886.2
• Gene: Socs1 / 252971
• RGDID: 69272
• Length: 212
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 70/253 - (27%)
• Similarity: 99/253 - (39%)
• Gaps: 60/253 - (23%)

  Fly   376 RNSVAVPDASHHHHQLIIRITSPGFVVESPNGGRVTVVTEPAPQSPQTPPRPRPLATV-APAGGA 439
            ||.||..:|           .||.    |....|....:..:..||..|.||||...| |||.|.
  Rat     4 RNQVAADNA-----------ISPA----SEPRRRPEPSSSSSSSSPAAPARPRPCPVVPAPAPGD 53

  Fly   440 GHAGIGAARNMTVHSQIDFMHCLVPDLEKITNSS-------FYWGKMDRYEAEHLLEGKPEGTFL 497
            .|     .|....||          |..:||.:|       ||||.:..:.|...|..:|.||||
  Rat    54 TH-----FRTFRSHS----------DYRRITRTSALLDACGFYWGPLSVHGAHERLRAEPVGTFL 103

  Fly   498 LRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKF-------SFDCHDPCVFTAPTVTGLLEHYKDP 555
            :|||.|....|:::.:........|:.....:|       :|||          :..|||||
  Rat   104 VRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRETFDC----------LFELLEHY--- 155

  Fly   556 ACVMFFEPCLTIPLHRRQTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYK 613
              |......|..||.:|:...||:|.|..||:....:.:.::.|...|:.||..:.::
  Rat   156 --VAAPRRMLGAPLRQRRVRPLQELCRQRIVAAVGRENLARIPLNPVLRDYLSSFPFQ 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589	31/113 (27%)
		SOCS	575..626	CDD:295349	10/39 (26%)
Socs1	NP_665886.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..57		22/72 (31%)
		Kinase inhibitory region (KIR)	56..67		4/20 (20%)
		Extended SH2 subdomain (ESS)	68..79		3/10 (30%)
		SH2_SOCS1	69..166	CDD:198245	30/111 (27%)
		SOCS	170..212	CDD:413360	11/42 (26%)
		Interaction with Elongin BC complex. /evidence=ECO:0000250	174..183		4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740