DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs36E and Tnp2

DIOPT Version :9

Sequence 1:	NP_523593.5	Gene:	Socs36E / 35085	FlyBaseID:	FBgn0041184	Length:	737	Species:	Drosophila melanogaster
Sequence 2:	NP_038722.3	Gene:	Tnp2 / 21959	MGIID:	98785	Length:	117	Species:	Mus musculus

Alignment Length:	135	Identity:	40/135 - (29%)
Similarity:	53/135 - (39%)	Gaps:	48/135 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LESLPVSNMLSAGTQH-----SSKPVSR-SNNSNSC-----CRSRSSKALSMGAATSSASG---- 291
            ::|||        |.|     ||:|.|. ||..|.|     ||| .|:|...|:::|.:.|
Mouse     5 MQSLP--------TTHPHPHSSSRPQSHTSNQCNQCTCSHHCRS-CSQAGHAGSSSSPSPGPPMK 60

  Fly   292 ----SASTSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSSSSSVSNKKDAAAVVAMVPRKSRT--A 350
                |..:..|.:..|.|..|. |.|....|          .||.:|       .|.|:.||  |
Mouse    61 HPKPSVHSRHSPARPSHRGSCP-KNRKTFEG----------KVSKRK-------AVRRRKRTHRA 107

  Fly   351 DRRST 355
            .|||:
Mouse   108 KRRSS 112

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589
Socs36E	NP_523593.5	SOCS	575..626	CDD:295349
Tnp2	NP_038722.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..117		40/135 (30%)
		TP2	1..113	CDD:279579	40/135 (30%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:P11101	90..98		4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900