Protein Alignment Socs36E and Socs2

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_017169385.1
• Gene: Socs2 / 216233
• MGIID: 1201787
• Length: 267
• Species: Mus musculus
• Alignment Length: 215
• Identity: 62/215 - (28%)
• Similarity: 94/215 - (43%)
• Gaps: 49/215 - (22%)

  Fly   430 LATVAPAG-GA-------GHAGI------GAARNMTVHSQIDFMHCLVPDLEKITNSSFYWGKMD 480
            |..:.|:| ||       |.||:      .|||             |...|.:::.:.:|||.|.
Mouse     3 LRCLEPSGNGADRTRSQWGTAGLPEEQSPEAAR-------------LAKALRELSQTGWYWGSMT 54

  Fly   481 RYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFD---CHDPCVFTA 542
            ..||:..|:..||||||:|||:..::|.:::.:......:.|||....||..|   |....:...
Mouse    55 VNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQF 119

  Fly   543 PTVTGLLEHY----KDP---------ACVMFFEPCLTIPLHRRQTFSLQQLSRATIVSNTSYDGI 594
            .:|..|:::|    ||.         ..|..:   ||.||:.... :||...|..|  |.....|
Mouse   120 DSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLY---LTKPLYTSAP-TLQHFCRLAI--NKCTGTI 178

  Fly   595 NQMELPGRLKSYLKEYHYKQ 614
            ..:.||.|||.||:||.:::
Mouse   179 WGLPLPTRLKDYLEEYKFQE 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	31/115 (27%)
		SOCS	575..626	CDD:470605	15/40 (38%)
Socs2	XP_017169385.1	SH2_SOCS2	40..142	CDD:198246	30/101 (30%)
		SOCS	158..197	CDD:470605	15/41 (37%)