Protein Alignment Socs36E and Cish

DIOPT Version :9

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_006511698.1
• Gene: Cish / 12700
• MGIID: 103159
• Length: 325
• Species: Mus musculus
• Alignment Length: 309
• Identity: 76/309 - (24%)
• Similarity: 120/309 - (38%)
• Gaps: 61/309 - (19%)

  Fly   357 PTLGTS-----SGGSQRRMQSQRIRNSVAVPDASHHHHQLIIRITS-PGFVVESPNGGRVTVVTE 415
            |.||:|     |||:. .:.|:...:......:.|.|....:..|. |.::|..|......:...
Mouse    25 PWLGSSYWHVFSGGTS-WLDSKTCTHRFLEHTSPHPHRDDTVADTPLPRYLVPRPLLAVEQIGRR 88

  Fly   416 PA-PQSPQTP-PRPRPLATVA-PAGGAGHAGIGAARNMTVHSQIDFMHCLVPDLEKITNSSFYWG 477
            |. .||.:.| |..:||.|.| |........:.|.....|......:.|:......:..|.:|||
Mouse    89 PLWAQSLELPGPAMQPLPTGAFPEEVTEETPVQAENEPKVLDPEGDLLCIAKTFSYLRESGWYWG 153

  Fly   478 KMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCH---DPCV 539
            .:...||...|:..||||||:|||....:||:::.:......:.|||.:...|..|.:   .|.:
Mouse   154 SITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRI 218

  Fly   540 FTAPTVTGLLEHY------------KDPACVMFFEPCLTIPLHRR-------------------- 572
            ...|.|..|::||            .|||      |...:|:.::
Mouse   219 LAFPDVVSLVQHYVASCAADTRSDSPDPA------PTPALPMSKQDAPSDSVLPIPVATAVHLKL 277

  Fly   573 -QTF-------SLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHYK 613
             |.|       |||.|.|  :|.|.....::.:.||.|:..||::|.::
Mouse   278 VQPFVRRSSARSLQHLCR--LVINRLVADVDCLPLPRRMADYLRQYPFQ 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:301589	32/114 (28%)
		SOCS	575..626	CDD:295349	14/46 (30%)
Cish	XP_006511698.1	SH2_CIS	145..232	CDD:198285	28/86 (33%)
		SOCS_CIS1	285..325	CDD:239703	13/42 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833073
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740