Protein Alignment Socs36E and socs7

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_012827004.2
• Gene: socs7 / 100158657
• XenbaseID: XB-GENE-969204
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 121/517 - (23%)
• Similarity: 176/517 - (34%)
• Gaps: 132/517 - (25%)

  Fly   141 VTNRTAGSSPEA--AKTERQPVNNNGLAGSVGAAISTLQLHDNHGGNANCPLEADDDDDLDESLL 203
            |.:|..|.:|||  |...|..|..|.|.|            :..||.|     |.:.:.|.|:|.
 Frog    16 VLSRLLGCAPEAEDAARPRLMVFRNMLRG------------EEEGGEA-----APEPEALVEALP 63

  Fly   204 RRRRSNSNSRSNIHHHHHHHQQQQQQQHEA-----------EVVEYCEVLESLPVSNML---SAG 254
            ......|....|.|..........:.|..|           |..:...|||: |.:..|   ..|
 Frog    64 AEGSPQSAELCNRHRKAAQPGLGLELQLGALGLRGAGCPCEETSDALLVLEA-PEARRLEEQEEG 127

  Fly   255 TQHSSKPVSRSNNSNSCCRSRSSKALSMGAATSSASGSASTSVSTSTSSKRRCCKCKCRDAIRGL 319
            ......|..|:.|..:..|:|.|:..    .|.|.:|...|:.
 Frog   128 EAAGQAPSRRAQNRKASLRNRLSRIF----RTKSCAGPPGTAE---------------------- 166

  Fly   320 RDMLPSSSSSVSNKKDAAAVVAMVPRKSRTADRRSTPPTLGTSSGGSQRRMQ----SQRIRNSVA 380
            |::..|..|.....:|....:...||.:||....| |.:......|....:.    |||..:|..
 Frog   167 RELGGSGGSLTDMSRDRELELGRKPRLTRTQSAFS-PVSFSPLFTGETVSLVDVDISQRGSSSTH 230

  Fly   381 VPDASHHHHQLIIRITSPGFVVESPNGGRVTVVTEPAPQ-SPQTPPRPRPLATVAPAGGAGHAGI 444
            .|             |.|      |...|...:.||.|: .|..|....|:..|.|
 Frog   231 PP-------------TPP------PPPRRSLSLLEPLPRLVPLRPTECVPVPLVQP--------- 267

  Fly   445 GAARNMTVHSQIDFMHC---------LVPDLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRD 500
                          :.|         ....|.::....:|||.|:..:||..|:.||:|:||:||
 Frog   268 --------------LQCPLFKQDPSSFAASLRELEKCGWYWGPMNWEDAEMKLKAKPDGSFLVRD 318

  Fly   501 SAQEEFLFSVTFRKYGRSLHARIEQSGHKFSFDCH----DPCVFTAPTVTGLLEHYKDPACVMFF 561
            |:...::.|::||..|.:.|.|:|.....||..||    |.|......:...:.|.|:...:.|.
 Frog   319 SSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFL 383

  Fly   562 E---------PC-LTIPLHR-RQTFSLQQLSRATIVSNTSYDGINQMELPGRLKSYLKEYHY 612
            .         |. |..|:.| ....|||.|.|..|......|.|.::.||..|.|||::::|
 Frog   384 RSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPELPLPKPLISYLRKFYY 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	32/112 (29%)
		SOCS	575..626	CDD:470605	15/38 (39%)
socs7	XP_012827004.2	SH2_SOCS7	281..381	CDD:198251	31/99 (31%)
		SOCS_SOCS7	405..453	CDD:239710	15/41 (37%)