Protein Alignment Socs36E and socs9

DIOPT Version :10

• Sequence 1: NP_523593.5
• Gene: Socs36E / 35085
• FlyBaseID: FBgn0041184
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001107273.1
• Gene: socs9 / 100003691
• ZFINID: ZDB-GENE-030131-4065
• Length: 497
• Species: Danio rerio
• Alignment Length: 546
• Identity: 187/546 - (34%)
• Similarity: 248/546 - (45%)
• Gaps: 128/546 - (23%)

  Fly   101 RQCADGATDDDAAALSADSLNANGQIVNVTLEGGYGEVGVVTNRTAGS------SPEAAKTERQ- 158
            |..:||....|  .||||.|:              || |...::||.|      .|..::|.||
Zfish    52 RPLSDGFEYGD--LLSADLLS--------------GE-GAALSQTASSRPPLVPDPGTSRTLRQK 99

  Fly   159 ---------PVNNNGLAGSVGAAISTLQLHDNHGGNANCPLEADDDDDLDESLLRRRRSNSNSRS 214
                     |:..:.|  |...|.|..::|.:......||..|..|......|::
Zfish   100 IQDAVGQCFPIKTHSL--SPAPAPSRRKIHLSELMLDRCPFPAGSDLAQKWYLIK---------- 152

  Fly   215 NIHHHHHHHQQQQQQQHEAEVVEYCEVLESLPVSNMLSAGTQHSSKPVSRSNNSNSCCRSRSSKA 279
                           ||.|.:  .|   .:.||...:||..:..|.|:...:....|
Zfish   153 ---------------QHTAPL--EC---ANTPVLECVSAPLECVSAPLECVSAPLEC-------- 189

  Fly   280 LSMGAATSSASGSASTSVSTSTSSKRRCCKCKCRDAIRGLRDMLPSSSSSVSNKKDAAAVVAMVP 344
              :||.....|......||.....:....:.:.|.:|.  :.:.|..::.:...:..|.:..:..
Zfish   190 --VGAPVECVSAPVLECVSAPLEDEEDRLRERRRISIE--QGVEPPPNAQIHTFEVTAQINPLYK 250

  Fly   345 RKSRTA--------DRRSTPPTLGTSSGGSQRRMQSQRIRNSVAVPDASHHHHQLIIRITSPGFV 401
            ...:.|        |.|:|                                .|||:::...
Zfish   251 LGPKLAHGMNELAGDERAT--------------------------------LHQLLLQTCL---- 279

  Fly   402 VESPNGGRVTVVTEPAPQSPQTPPRPRPLATVAPAGGAGHAGIGAARNMTVHSQIDFMHCLVPDL 466
                  ..:..|...||.|....|... :.|.||:.....:.........||:|||::|||||||
Zfish   280 ------DTLDEVAASAPVSVSAVPDVE-ICTAAPSVIRSESPKTQDYQHRVHTQIDYIHCLVPDL 337

  Fly   467 EKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGHKFS 531
            .:|||.|.|||.|||||||.||||||||||||||||||::||||:||:|||||||||||..|.||
Zfish   338 LEITNLSCYWGVMDRYEAETLLEGKPEGTFLLRDSAQEDYLFSVSFRRYGRSLHARIEQWNHNFS 402

  Fly   532 FDCHDPCVFTAPTVTGLLEHYKDPACVMFFEPCLTIPLHRRQTFSLQQLSRATIVSNTSYDGINQ 596
            ||.|||.||.||||||||||||||...|||||.|:.|:||.|.||||::.||.|.|.:|||||..
Zfish   403 FDVHDPSVFHAPTVTGLLEHYKDPNSCMFFEPLLSNPIHRTQPFSLQRICRAVISSRSSYDGIGT 467

  Fly   597 MELPGRLKSYLKEYHYKQKLRVKPID 622
            :.||..||.:||||||||::|::.:|
Zfish   468 LPLPAALKEHLKEYHYKQRVRIRRLD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs36E	NP_523593.5	SH2	463..563	CDD:472789	80/99 (81%)
		SOCS	575..626	CDD:470605	27/48 (56%)
socs9	NP_001107273.1	SOCS	<74..114	CDD:432667	8/39 (21%)
		SH2	334..434	CDD:472789	80/99 (81%)
		SOCS	443..493	CDD:470605	27/49 (55%)