Protein Alignment kel and klhl20

DIOPT Version :10

• Sequence 1: NP_476589.4
• Gene: kel / 35084
• FlyBaseID: FBgn0001301
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_998166.2
• Gene: klhl20 / 406274
• ZFINID: ZDB-GENE-040426-1935
• Length: 591
• Species: Danio rerio
• Alignment Length: 590
• Identity: 252/590 - (42%)
• Similarity: 366/590 - (62%)
• Gaps: 21/590 - (3%)

  Fly   102 CLLRYASQNSLDESSQKHVQRPNGKERGTVGQYSNEQHTARSFDAMNEMRKQKQLCDVILVADDV 166
            |.|  ...|.|.|...:..:.|          |.:::|..::.:.:|.:||.::||||:||....
Zfish     7 CTL--GDPNKLPEGVPQPARMP----------YISDKHPRQTLEVINLLRKHRELCDVVLVVGAK 59

  Fly   167 EIHAHRMVLASCSPYFYAMFT-SFEESRQARITLQSVDARALELLIDYVYTATVEVNEDNVQVLL 230
            :|:|||::|::|||||.|||| ...||||..:.::.:|.||:|||||:.||:.|.|.|.|||.||
Zfish    60 KIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLL 124

  Fly   231 TAANLLQLTDVRDACCDFLQTQLDASNCLGIREFADIHACVELLNYAETYIEQHFNEVIQFDEFL 295
            .||.||||.::::|||:||:.|||.|||||||.|||.|:|.|||..|:.:.:.:|.||::.:||:
Zfish   125 PAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFM 189

  Fly   296 NLSHEQVISLIGNDRISVPNEERVYECVIAWLRYDVPMREQFTSLLMEHVRLPFLSKEYITQRVD 360
            .|...|:|.:|.:|.::|.:||:|:..|:||::|.:..|......:::|||||.||.:::...|.
Zfish   190 LLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVG 254

  Fly   361 KEILLEGNIVCKNLIIEALTYHLLPTE---TKSARTVPRKPVGMPKILLVIGGQ-APKAIRSVEW 421
            .:.|::.:..|::|:.||..|.|||.|   .:..||.||||:...::|..:||. :..||.|||.
Zfish   255 SDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVER 319

  Fly   422 YDLREEKWYQAAEMPNRRCRSGLSVLGDKVYAVGGFNGSLRVRTVDVYDPATDQW-ANCSNMEAR 485
            ||.:..:|...|.|..|||..|:|||.|.:|||||.:||..:.:|:.|||.|:|| ::.:.....
Zfish   320 YDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTC 384

  Fly   486 RSTLGVAVLNGCIYAVGGFDGTTGLSSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGG 550
            |:::|||||.|.:|||||.||.:.|:..|.||||.:.|..:|||||||..|.|.|:.|.||||||
Zfish   385 RTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGG 449

  Fly   551 YDGFTRQCLSSVERYNPDTDTWVNVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVRRSVEAYDCE 615
            .||.:.  |::||||||..:.|..||.|.:||...|..|..:::|:|||.|......|.|.|:..
Zfish   450 SDGTSP--LNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPR 512

  Fly   616 TNSWRSVADMSYCRRNAGVVAHDGLLYVVGGDDGTSNLASVEVYCPDSDSWRILPALMTIGRSYA 680
            ||.|..|..|:..|...|:...:|.|..|||.|||:.|.::|||.||:::||:... |...|...
Zfish   513 TNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGG-MNYRRLGG 576

  Fly   681 GVCMI 685
            ||.:|
Zfish   577 GVGVI 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kel	NP_476589.4	BTB_POZ_KLHL2-like	136..255	CDD:349544	59/119 (50%)
		PHA03098	150..675	CDD:222983	239/530 (45%)
		KELCH repeat	439..482	CDD:276965	21/43 (49%)
		KELCH repeat	486..530	CDD:276965	23/43 (53%)
		KELCH repeat	533..580	CDD:276965	24/46 (52%)
		KELCH repeat	582..626	CDD:276965	15/43 (35%)
		KELCH repeat	629..674	CDD:276965	18/44 (41%)
klhl20	NP_998166.2	None