Protein Alignment kel and klhl10

DIOPT Version :10

• Sequence 1: NP_476589.4
• Gene: kel / 35084
• FlyBaseID: FBgn0001301
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Alignment Length: 746
• Identity: 199/746 - (26%)
• Similarity: 333/746 - (44%)
• Gaps: 103/746 - (13%)

  Fly   143 SFDAMNEMRKQKQLCDV-ILVADDVEIHAHRMVLASCSPYFYAMFTSFE-------ESRQAR--- 196
            :.:.:||:|:|..|||. |.|.:|| .:.||.::.|||.||.|.||.|.       :...|:
  Fly    68 ALNTLNELREQNLLCDAQISVGEDV-FNVHRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKKNN 131

  Fly   197 --ITLQSVDARALELLIDYVYTATVEVNEDNVQVLLTAANLLQLTDVRDACCDFLQTQLDASNCL 259
              |.:..|.:..:..:|.|.|.....::|.||..||..|:.:.:..:...|.|:|...|...||:
  Fly   132 NFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTPENCV 196

  Fly   260 GIREFADIHACVELLNYAETYIEQHFNEVIQFD-EFLNLSHEQVISLIGNDRISVPNEERVYECV 323
            .|..||......:|...|..|..::|.||...: :.|::|.|...|:|.:|.::...|:.|::..
  Fly   197 SIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHVWKLC 261

  Fly   324 IAWLRYDVPMREQFTSLLMEHVRLPFLSKEYITQRVDKEILLEGNIVCKNLIIEALTY-HLLPTE 387
            :.|:..:...|::..:.||..|||..::.:...:.|.:...:......|.||::...: :.|...
  Fly   262 VKWIDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFL 326

  Fly   388 TKSARTVPRKPVGMPK----ILLVIGGQAPKAIRS-VEWYDLREEKW--YQAAEMPNRRCRSGLS 445
            ...|..:...|:.||:    ::..|||.:....:. :|.||.|.::|  ..|.:....|...|.:
  Fly   327 NPQADELTTPPLAMPRLPHEVIFAIGGWSGGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTA 391

  Fly   446 VLGDKVYAVGGFNGSLRVRTVDVYDPATDQWANCSNMEARRSTLGVAVLNGCIYAVGGFDGTTGL 510
            |||.|::::||::|.....|..|:|....:|...:.|..||..:.|..|||.|||:||:||...|
  Fly   392 VLGFKIFSIGGYDGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGHNRL 456

  Fly   511 SSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGGYDGFTRQCLSSVERYNPDTDTWVNV 575
            ::.|.|:|:|:.|..|..|:.:||......:...:||.||::|  ::||.|.|.|:|.|:.|..:
  Fly   457 NTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNG--QECLDSAEYYDPVTNVWTRI 519

  Fly   576 AEMSSRRSGAGVGVLNNILYAVGGHDGPMVRRSVEAYDCETNSWRSVADMSYCRRNAGVVAHDGL 640
            ..|:.||||.......|.||.:||.:|.....:.|.:|.:|.:|..:.:|::.|.|.|:...|.:
  Fly   520 PNMNHRRSGVSCVAFRNQLYVIGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDDM 584

  Fly   641 LYVVGGDDGTSNLASVEVYCPDSDSWRILPAL-MTIGRSYAGVCMI------------DKPMXME 692
            ::.:||.:|.|.::..|.|..::|.|  :.|. |.|.||......|            ::.. ||
  Fly   585 IFAIGGFNGVSTISHTECYVAETDEW--MEATDMNIVRSALSANNIAGLPNKRDYIHKERDRLME 647

  Fly   693 EQGALARQAASLAIALLDDENSQAEGTMEGAIGGAIYGNLAPAGGAAAAAAPAAPAQAPQPNHPH 757
            |     |:...:|.|:..:.           :|   :||                  |.|....|
  Fly   648 E-----RRQRLMATAMAREN-----------VG---HGN------------------ASQMLVEH 675

  Fly   758 YENIYAPIGQPSNNNNNSGSNSNQAAAIANANAPANAEEIQQQQQPA---PTEPNANNNPQPPTA 819
                            |.|       |:.:..:|...:|..:|:|.|   .|.|.:...|.|..|
  Fly   676 ----------------NDG-------AMDDYESPDEVDETDEQEQSARISRTIPPSVGLPNPAVA 717

  Fly   820 AAPAPSQQQQQQQAQPQQPQRILPMNNYRND 850
            |.....|.|....||..:......|:|.|::
  Fly   718 AETIRDQSQLVSTAQLNRVMEDRGMDNNRSN 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kel	NP_476589.4	BTB_POZ_KLHL2-like	136..255	CDD:349544	38/124 (31%)
		PHA03098	150..675	CDD:222983	160/547 (29%)
		KELCH repeat	439..482	CDD:276965	13/42 (31%)
		KELCH repeat	486..530	CDD:276965	19/43 (44%)
		KELCH repeat	533..580	CDD:276965	16/46 (35%)
		KELCH repeat	582..626	CDD:276965	13/43 (30%)
		KELCH repeat	629..674	CDD:276965	13/45 (29%)
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	17/40 (43%)
		PHA03098	86..610	CDD:222983	152/526 (29%)
		KELCH repeat	385..428	CDD:276965	13/42 (31%)
		KELCH repeat	432..475	CDD:276965	19/42 (45%)
		KELCH repeat	479..523	CDD:276965	15/45 (33%)
		KELCH repeat	526..571	CDD:276965	14/44 (32%)
		KELCH repeat	573..617	CDD:276965	13/45 (29%)