Protein Alignment CG5758 and TGFBI

DIOPT Version :9

• Sequence 1: NP_001286028.1
• Gene: CG5758 / 35083
• FlyBaseID: FBgn0032666
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_000349.1
• Gene: TGFBI / 7045
• HGNCID: 11771
• Length: 683
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 112/572 - (19%)
• Similarity: 204/572 - (35%)
• Gaps: 135/572 - (23%)

  Fly    26 AASATAADATAATAASTTSTGIDASLKNAKLIEAKVLPDLAILQRVNQEDEKW----QQVYRFID 86
            |.:...|...|||.|....:.....|::::|...:..|::..:|:|...:.|:    :|.|:...
Human     9 ALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKI 73

  Fly    87 DGFPVLELY----GYKPLPD-------LPYTLIVPKIDVRSIEKPRLKEFMLEHVVPGKIFDSYN 140
            .|...:..|    ||:.:|.       ||.:.:...:.|......:|.....|.:.|
Human    74 CGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRP-------- 130

  Fly   141 GNGNSKEEEESFGNGNGHKIVFRKLEKSHNNVWLLNGQQILHKLRINENLMAI-AIDGYLGDRK- 203
                   |.|    |.|...:|    ...|..|.....::|..|..|.|:..: |:..::..|:
Human   131 -------EME----GPGSFTIF----APSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180

  Fly   204 ------------SPYSKRNIQETNNRYNDPQPLEQPNI-----TNAHAK------VEPVIKESKA 245
                        |.|...|||    .::.|..:...|.     .:.||.      ::.||  |..
Human   181 LTDELKHGMTLTSMYQNSNIQ----IHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVI--STI 239

  Fly   246 SPLMSFLANMKTGTKVFQHFLSKSNLTRIMDDNA-YTVLIPSDNAFQRWHPIDWGFYPFSV---- 305
            :..:..:..::...:..:..::.|.|..:::.|. ||:|.|::.||::        .|...
Human   240 TNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEK--------IPSETLNRI 296

  Fly   306 ---PEFTESVLRNHFLPMQRPLRLADVRNMDEVVVTTMGGEDVVFHGQPTPTVNNVSIMSDYNLS 367
               ||....:|.||.|....         ..|.:|..:..|.:      ..|...|....|....
Human   297 LGDPEALRDLLNNHILKSAM---------CAEAIVAGLSVETL------EGTTLEVGCSGDMLTI 346

  Fly   368 NGNQVFIISEVLFVTEAVVSKLHQMHKDKETPPLLAFPWFGAQFLSHSFLALERDPRFTQITRYL 432
            ||..:....::| .|..|:..:.::........|..             ||.|.|.. |.|..:
Human   347 NGKAIISNKDIL-ATNGVIHYIDELLIPDSAKTLFE-------------LAAESDVS-TAIDLF- 395

  Fly   433 NSAEIAPHISGA-NYTFFVPEDRAFEKQGFDKLSDEVMASQRGVKMLLNHFVKGRLYNRDLRDNE 496
            ..|.:..|:||: ..|...|.:..| |.|    :..:.|..|  .:|.||.:|.:|.::.|...:
Human   396 RQAGLGNHLSGSERLTLLAPLNSVF-KDG----TPPIDAHTR--NLLRNHIIKDQLASKYLYHGQ 453

  Fly   497 VFETIGGGHIKITRNPGSNYTSVNNAQITESEVFVYN----LGTMYYLDDIL 544
            ..||:||..:::       :...|:..|..|.:..::    .||::.:|.:|
Human   454 TLETLGGKKLRV-------FVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_001286028.1	FAS1	281..380	CDD:214719	20/105 (19%)
		FAS1	447..545	CDD:214719	24/102 (24%)
TGFBI	NP_000349.1	Fasciclin	133..236	CDD:396845	21/114 (18%)
		Fasciclin	253..373	CDD:396845	27/143 (19%)
		Fasciclin	386..500	CDD:396845	31/129 (24%)
		Fasciclin	514..634	CDD:396845
		Cell attachment site. /evidence=ECO:0000255	642..644

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10900
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010