DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5758 and Postn

DIOPT Version :9

Sequence 1:	NP_001286028.1	Gene:	CG5758 / 35083	FlyBaseID:	FBgn0032666	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001355607.1	Gene:	Postn / 50706	MGIID:	1926321	Length:	838	Species:	Mus musculus

Alignment Length:	415	Identity:	82/415 - (19%)
Similarity:	154/415 - (37%)	Gaps:	103/415 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 GHKIVFRKLEKSHNNVWLLNGQQILHKLRINENLMAIAI----DG---YLGDRKSPYSKRNIQET 214
            |.|:....|.|.|          ||:.|:.:|.:...|:    :|   .:|......|...|:..
Mouse   294 GDKVASEALMKYH----------ILNTLQCSEAITGGAVFETMEGNTIEIGCEGDSISINGIKMV 348

  Fly   215 NNRYNDPQPLEQPNITNAHA---KVEPVIKESKASPLMSFLANMKTGTKVFQHFLSKSNL-TRIM 275
            |.:          :|...:.   .::.|:....|..::......:|   .|...:::..| :.:.
Mouse   349 NKK----------DIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT---TFTDLVAQLGLASSLK 400

  Fly   276 DDNAYTVLIPSDNAF--------QRWHPIDWGFYPFSVPEFTESVLRNHFLPMQRPLRLADVRNM 332
            .|..||:|.|.:|||        ||               ..:.:|:||.|.::  :.|:|:.|.
Mouse   401 PDGEYTLLAPVNNAFSDDTLSMDQR---------------LLKLILQNHILKVK--VGLSDLYNG 448

  Fly   333 DEVVVTTMGGEDV-VFHGQPTPTVNNVSIMSDYNLSNGNQVFIISEVLFVTEAVVSKLHQMHKDK 396
            .  ::.|:||:.: ||..:....:.|..::..........:.|..|::...|   ..||    ||
Mouse   449 Q--ILETIGGKQLRVFVYRTAICIENSCMVRGSKQGRNGAIHIFREIIQPAE---KSLH----DK 504

  Fly   397 ETPPLLAFPWFGAQFLSHSFLALERDPRFTQITRYLNSAEIAPHIS-GANYTFFVPEDRAFEKQG 460
                                  |.:|.||:.....|.:|::...:: ..::|.|.|.:.||  :|
Mouse   505 ----------------------LRQDKRFSIFLSLLEAADLKDLLTQPGDWTLFAPTNDAF--KG 545

  Fly   461 FDKLSDEVMASQRGV--KMLLNHFVKGRLYNRDLRD--NEVFETIGGGHIKITRNPGSNYT-SVN 520
            ......|::...:..  .::|.|...|....:....  ..:.:|..|..|.:   .|.|.| .||
Mouse   546 MTSEERELLIGDKNALQNIILYHLTPGVYIGKGFEPGVTNILKTTQGSKIYL---KGVNETLLVN 607

  Fly   521 NAQITESEVFVYNLGTMYYLDDILY 545
            ..:..||::...| |.::.:|.:||
Mouse   608 ELKSKESDIMTTN-GVIHVVDKLLY 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_001286028.1	FAS1	281..380	CDD:214719	23/107 (21%)
CG5758	NP_001286028.1	FAS1	447..545	CDD:214719	23/102 (23%)
Postn	NP_001355607.1	Fasciclin	111..232	CDD:308211
		Fasciclin	247..369	CDD:308211	17/94 (18%)
		Fasciclin	384..496	CDD:308211	28/133 (21%)
		Fasciclin	509..632	CDD:308211	29/129 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	811..838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10900
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010