DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5758 and Postn

DIOPT Version :9

Sequence 1:	NP_001286028.1	Gene:	CG5758 / 35083	FlyBaseID:	FBgn0032666	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_006232397.1	Gene:	Postn / 361945	RGDID:	1305285	Length:	838	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	80/415 - (19%)
Similarity:	153/415 - (36%)	Gaps:	103/415 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 GHKIVFRKLEKSHNNVWLLNGQQILHKLRINENLMAIAI----DG---YLGDRKSPYSKRNIQET 214
            |.|:....|.|.|          ||:.|:.:|.:...|:    :|   .:|......|...|:..
  Rat   294 GDKVASEALMKYH----------ILNTLQCSEAITGGAVFETMEGNTIEIGCEGDSISINGIKMV 348

  Fly   215 NNRYNDPQPLEQPNITNAHA---KVEPVIKESKASPLMSFLANMKTGTKVFQHFLSKSNL-TRIM 275
            |.:          :|...:.   .::.|:....|..::......:|   .|...:::..| :.:.
  Rat   349 NKK----------DIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT---TFTDLVAQLGLASSLK 400

  Fly   276 DDNAYTVLIPSDNAF--------QRWHPIDWGFYPFSVPEFTESVLRNHFLPMQRPLRLADVRNM 332
            .|..||:|.|.:|||        ||               ..:.:|:||.|.::  :.|:|:.|.
  Rat   401 PDGEYTLLAPVNNAFSDDTLSMDQR---------------LLKLILQNHILKVK--VGLSDLYNG 448

  Fly   333 DEVVVTTMGGEDV-VFHGQPTPTVNNVSIMSDYNLSNGNQVFIISEVLFVTEAVVSKLHQMHKDK 396
            .  ::.|:||:.: ||..:....:.|..::..........:.|..|::...|   ..||:
  Rat   449 Q--ILETIGGKQLRVFVYRTAICIENSCMVRGSKQGRNGAIHIFREIIQPAE---KSLHE----- 503

  Fly   397 ETPPLLAFPWFGAQFLSHSFLALERDPRFTQITRYLNSAEIAPHIS-GANYTFFVPEDRAFEKQG 460
                                 .|.:|.||:.....|.:|::...:: ..::|.|.|.:.||  :|
  Rat   504 ---------------------KLRQDKRFSIFLSLLEAADLKDLLTQPGDWTLFAPTNDAF--KG 545

  Fly   461 FDKLSDEVMASQRGV--KMLLNHFVKGRLYNRDLRD--NEVFETIGGGHIKITRNPGSNYT-SVN 520
            ......|::...:..  .::|.|...|....:....  ..:.:|..|..|.:   .|.|.| .||
  Rat   546 MTNEEREILIGDKNALQNIILYHLTPGVYIGKGFEPGVTNILKTTQGSKIYV---KGVNETLLVN 607

  Fly   521 NAQITESEVFVYNLGTMYYLDDILY 545
            ..:..||::...| |.::.:|.:||
  Rat   608 ELKSKESDIMTTN-GVIHVVDKLLY 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_001286028.1	FAS1	281..380	CDD:214719	23/107 (21%)
CG5758	NP_001286028.1	FAS1	447..545	CDD:214719	23/102 (23%)
Postn	XP_006232397.1	Fasciclin	111..232	CDD:396845
		Fasciclin	247..369	CDD:396845	17/94 (18%)
		Fasciclin	384..496	CDD:396845	28/133 (21%)
		Fasciclin	509..632	CDD:396845	29/129 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10900
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010