Protein Alignment CG5758 and tgfbi

DIOPT Version :10

• Sequence 1: NP_609866.1
• Gene: CG5758 / 35083
• FlyBaseID: FBgn0032666
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_878282.1
• Gene: tgfbi / 321421
• ZFINID: ZDB-GENE-030131-73
• Length: 677
• Species: Danio rerio
• Alignment Length: 601
• Identity: 111/601 - (18%)
• Similarity: 202/601 - (33%)
• Gaps: 182/601 - (30%)

  Fly    12 TLVLLSLLPIAHVAAASATAADATAATAASTTSTGIDASLKNAKLIEAKVLPDLAILQRVNQEDE 76
            ||..|::..||.|.||.:.                ..|.|:::::......|::..:|::...|:
Zfish     5 TLFALAITLIATVFAAKSP----------------YQAVLQHSRIRGRTQGPNVCAMQKIPGSDK 53

  Fly    77 KW----QQVYRFIDDGFPVLELY----GY-KPLPDLPYTLIVPKIDVRSIEKPRLKEFMLEHVVP 132
            |:    :|.||....|.|.:..|    || |.:.:......:|.:::          :....||.
Zfish    54 KYFTNCKQWYRRKICGKPTVISYECCPGYEKVIGEKGCPAALPLVNI----------YKTLSVVE 108

  Fly   133 GKIFDSYNGNGNSKEEEESFGNGNGHKIVFRKLEK--------------SHNNVWLLNGQQILHK 183
            ......|:.....:||.|    |.|....|....:              |:.|:.|||.   ||.
Zfish   109 ATTTKMYSERAKLQEEIE----GPGSFTFFAPSNEAWAPLPTEILDALVSNVNIELLNA---LHY 166

  Fly   184 LRINENLMA-----------------IAIDGYLGDRKSPYSKRNIQETNNRYNDPQPLEQPNITN 231
            ..||:.|.:                 :.|..|.....:....|.::...:..|....:....||.
Zfish   167 HMINKRLTSEDLKHGSSFSSMHQDFDVHIHHYSNGIVTVNCARLVKTDQHATNGIVHVVDRVITA 231

  Fly   232 AHAKVEPVIKESKASPLMSFLANMKTGTKVFQHFLSKSNLTRIMDD-NAYTVLIPSDNAFQRWHP 295
            ....|..:|...      ..|..::|.       ::.:.||.:::: .:||:..|::.||::
Zfish   232 ITNDVNSIIDTD------DDLDTLRTA-------VAAAGLTTLLENQGSYTIFAPTNEAFEK--- 280

  Fly   296 IDWGFYPFSVPEFTESVLRNHFLPMQRPLRLADVRNM--------DEVVV------TTMG----- 341
                 .|   |:....:|.:       |:.|.|:.|.        .|.:|      |..|
Zfish   281 -----IP---PDTLTRILGD-------PVALKDLLNFHILKNLHCSESIVAGTPLETLQGTMLEV 330

  Fly   342 ---GEDVVFHGQPTPTVNNVSIMSDYNLSNGNQVFIISEVLFVTEAVVSKLHQMHKDKETPPLLA 403
               |||:..:|:...|..:       .|.....|..|:|:|....|
Zfish   331 GCDGEDLTINGKAVVTQKD-------KLGTNGVVHYINELLIPDSA------------------- 369

  Fly   404 FPWFGAQFLSHSFLALERDPRFTQITRYLNSAEIAPHISGA-NYTFFVPEDRAFEKQGFDKLSDE 467
                      .:.|.|......|...:....|.:..|:.|: :.|...|.:.||:.:.|....|.
Zfish   370 ----------KTLLELAEGSVVTTAAKLFKDAGLNDHLVGSESVTLLAPLNEAFKDKSFAMTPDM 424

  Fly   468 VMASQRGVKMLLNHFVKGRLYNRDLRDNEVFETIGGGHIKITRNPGSNYTSVNNAQITESEVFVY 532
                   .|:|.||.:|.:..::.|...:..||:||..:::       :...||..|..:.:..:
Zfish   425 -------KKLLRNHILKEKFSSKSLYHGQELETLGGLKLRV-------FVFRNNLCIENACIAAH 475

  Fly   533 N----LGTMYYLDDIL 544
            :    ...|:.:|.||
Zfish   476 DKNGRYANMFLVDSIL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_609866.1	FAS1	281..380	CDD:214719	24/120 (20%)
		FAS1	447..545	CDD:214719	23/102 (23%)
tgfbi	NP_878282.1	Fasciclin	110..229	CDD:396845	21/125 (17%)
		Fasciclin	250..366	CDD:396845	29/147 (20%)
		Fasciclin	382..493	CDD:396845	27/124 (22%)
		FAS1	492..627	CDD:441906	111/601 (18%)