Protein Alignment CG5758 and Tgfbi

DIOPT Version :10

• Sequence 1: NP_609866.1
• Gene: CG5758 / 35083
• FlyBaseID: FBgn0032666
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_446254.1
• Gene: Tgfbi / 116487
• RGDID: 620017
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 118/577 - (20%)
• Similarity: 217/577 - (37%)
• Gaps: 127/577 - (22%)

  Fly    14 VLLSLLPIAHVAAASATAADATAATAASTTSTGIDASLKNAKLIEAKVLPDLAILQRVNQEDEKW 78
            :|:.|||:|...:...|      .|.|....:.....|::::|...:..|::..:|:|...::|:
  Rat     3 LLVRLLPLALALSLGFT------GTLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNKKY 61

  Fly    79 ----QQVYRFIDDGFPVLELY----GYKPLPD-------LPYTLIVPKIDVRSIEKPRLKEFMLE 128
                :|.|:....|...:..|    ||:.:|.       ||.:.:...:.:......:|.....|
  Rat    62 FTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGIVGSTTTQLYTDRTE 126

  Fly   129 HVVPGKIFDSYNGNGNSKEEEESFGNGNGHKIVFRKLEKSHNNVWLLNGQQILHKLRINENLMAI 193
            .:.|               |.|    |.|...:|    ...|..|.....::|..|..|.|:..:
  Rat   127 KLRP---------------EME----GPGSFTIF----APSNEAWSSLPAEVLDSLVSNVNIELL 168

  Fly   194 -AIDGYLGDRK-------------SPYSKRNIQETNNRYNDPQPLEQPNI-----TNAHAK---- 235
             |:..::.||:             |.|...|||    .::.|..:...|.     .:.||.
  Rat   169 NALRYHMVDRRVLTDELKHGMALTSMYQNSNIQ----IHHYPNGIVTVNCARLLKADHHATNGVV 229

  Fly   236 --VEPVIKESKASPLMSFLANMKTGTKVFQHFLSKSNLTRIMD-DNAYTVLIPSDNAFQRWHPID 297
              ::.||  |..:..:..:..::...:..:..::.|.|..::: |..:|:|.|::.||:: .|.:
  Rat   230 HLIDKVI--STVTNNIQQIIEIEDTFETLRAAVAASGLNTVLEGDGQFTLLAPTNEAFEK-IPAE 291

  Fly   298 WGFYPFSVPEFTESVLRNHFLPMQRPLRLADVRNMDEVVVTTMGGEDVVFHGQPTPTVNNVSIMS 362
            ........||....:|.||.|....... |.|..|   .:.|:||           |...|....
  Rat   292 TLNRILGDPEALRDLLNNHILKTAMCAE-AIVAGM---AMETLGG-----------TTLEVGCSG 341

  Fly   363 DYNLSNGNQVFIISEVLFVTEAVVSKLHQMHKDKETPPLLAFPWFGAQFLSHSFLALERDPRFTQ 427
            |....||..|....::| .|..|:..:.::........||.             ||.|.|  .:.
  Rat   342 DMLTINGKAVISNKDIL-ATNGVIHFIDELLIPDSAKTLLE-------------LASESD--VST 390

  Fly   428 ITRYLNSAEIAPHISG-ANYTFFVPEDRAFEKQGFDKLSDEVMASQRGVKMLLNHFVKGRLYNRD 491
            ....|..|.::.|:|| ...||..|.:..| |.|..::..::..      :||||.|||:|.::.
  Rat   391 AIDLLRQAGLSTHLSGKEQLTFLAPLNSVF-KDGVPRIDGQMKT------LLLNHMVKGQLASKY 448

  Fly   492 LRDNEVFETIGGGHIKITRNPGSNYTSVNNAQITESEVFVYN----LGTMYYLDDIL 544
            |...:..:|:||..:::       :...|:..|..|.:..::    .||::.:|.:|
  Rat   449 LYSGQTLDTLGGKKLRV-------FVYRNSLCIENSCIAAHDKKGRYGTLFTMDRML 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_609866.1	FAS1	281..380	CDD:214719	24/98 (24%)
		FAS1	447..545	CDD:214719	25/102 (25%)
Tgfbi	NP_446254.1	Fasciclin	133..236	CDD:396845	22/114 (19%)
		Fasciclin	253..373	CDD:396845	30/136 (22%)
		Fasciclin	386..500	CDD:396845	31/129 (24%)
		FAS1	499..634	CDD:441906	118/577 (20%)