DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5758 and postn

DIOPT Version :9

Sequence 1:	NP_001286028.1	Gene:	CG5758 / 35083	FlyBaseID:	FBgn0032666	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001106376.1	Gene:	postn / 100127174	XenbaseID:	XB-GENE-478502	Length:	795	Species:	Xenopus tropicalis

Alignment Length:	303	Identity:	64/303 - (21%)
Similarity:	125/303 - (41%)	Gaps:	62/303 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 GTKVFQHFLSKSNLTRIMDD-NAYTVLIPSDNAFQRWHPIDWGFYPFSVPEFTESVLRN------ 315
            |....|.:..:|.|.:.::. .:||...||::|   |..:|        .:..:|:|.|
Frog   110 GATSTQDYSDRSELRKEIEGVGSYTFFAPSNDA---WQLLD--------SDVRDSLLSNVNIELL 163

  Fly   316 ---HFLPMQRPLRLADVRNMDEVVVTTM--GGEDVVFHGQPTPTVNNVSIMSDYNLSNGNQVFII 375
               |:..:.:.:...|::|  .:.||:|  ..|.|:.|     ..|.|..::...:.:|||: ..
Frog   164 NALHYHMINKRMLTKDLKN--GLSVTSMFNNQELVINH-----YTNGVVTVNCARVIHGNQI-AT 220

  Fly   376 SEVLFVTEAVVSKLHQMHKDKETPPLLAFPWFGAQFLSHSFLALERDPRFTQITRYLNSAEIAPH 440
            :.|:.|.:.||:.:....:|                      .:|.:...|.......:||:...
Frog   221 NGVVHVIDRVVTAVGNTIED----------------------FIESEDELTSFREAGVAAEVLAE 263

  Fly   441 I-SGANYTFFVPEDRAFEK--QGFDKLSDEVMASQRGVKMLLN-HFVKGRLYNRDLRDNEVFETI 501
            : ....||.|.|.:.||||  :|   :.:.:||.::.||.|:| |.:.....:..:....:.||:
Frog   264 LGKKGQYTLFAPTNDAFEKLPRG---VLERIMADKQAVKALVNYHILNSVQCSEAIMGGSLLETL 325

  Fly   502 GGGHIKITRNPGSNYTSVNNAQITESEVFVYNLGTMYYLDDIL 544
            .|..::|..: |.:.|...|..:...::...| |.::.:|.:|
Frog   326 EGSSLQIGCD-GDSLTVNGNKMVNRKDIVTTN-GVIHLIDQVL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5758	NP_001286028.1	FAS1	281..380	CDD:214719	24/109 (22%)
CG5758	NP_001286028.1	FAS1	447..545	CDD:214719	26/101 (26%)
postn	NP_001106376.1	Fasciclin	110..230	CDD:308211	30/138 (22%)
		Fasciclin	246..368	CDD:308211	30/126 (24%)
		Fasciclin	383..495	CDD:308211
		Fasciclin	508..632	CDD:308211
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10900
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100