Protein Alignment CG31741 and SCARB2

DIOPT Version :9

• Sequence 1: NP_724088.2
• Gene: CG31741 / 35079
• FlyBaseID: FBgn0051741
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 115/486 - (23%)
• Similarity: 214/486 - (44%)
• Gaps: 48/486 - (9%)

  Fly     5 CCSVRQQKIWVFSMGG------LILAIGIFLASAWPAVSRQWIRSLLPLAPNSFIYNRWVTTPTP 63
            ||         |...|      |:.::.:.:|..:.....|.|...:.|...:..::.|...|.|
Human     4 CC---------FYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLP 59

  Fly    64 VYSTVFLFNWTNPGDLNTEGVKPHFEQLGPYTFSDFKVKEDLEW--NQPQVTYFGKRTWHFLPEK 126
            ||:..:.||.|||.:: ..|..|..|::||||:.:.:.|.::::  |...::....:.:.|..::
Human    60 VYTQFYFFNVTNPEEI-LRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQ 123

  Fly   127 SNGSLD-DVVIAPHFPTLTAALYSRRLRRILRKVMNFTLNREGGATHMTHTAGQWLFDGYYDHLL 190
            |.|... |::...:.|.||...:|:  ...||:::...|........:|||..:.|: ||.|.:|
Human   124 SVGDPKIDLIRTLNIPVLTVIEWSQ--VHFLREIIEAMLKAYQQKLFVTHTVDELLW-GYKDEIL 185

  Fly   191 DFVEQLHSPLLPVYDNTFGWFYERNNSKTAEGNFTLHTGRGDLSQLGDLLLWNGENTTGFY-PGE 254
            ..:......:.|.    ||.|||:|.  |.:|::...||.........::.|||:.:..:: ..:
Human   186 SLIHVFRPDISPY----FGLFYEKNG--TNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDK 244

  Fly   255 CGKVNGSTGELWSPYRTWDQPTTIFLPDAARYLNLFPKENLTIDGIDVWRYESTNLTIDNGQLSP 319
            |..:||:.|:.:.|..|.|:...:|..|..|.:.:...:..::.|:..:||:.....:.|   :.
Human   245 CNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILAN---TS 306

  Fly   320 DTECFCLKNRECPRNGVLDYGPPAFNGPFYMSHPHFFLTDQMYRENTTGLQPEESEHGMYVIMEP 384
            |...||:....|..:|||:........|..||.|||:..|:.:.....|:.|.:.:|..:|.:.|
Human   307 DNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINP 371

  Fly   385 TLGIPL--SLRGQLMISTKVVRD--EAIDLFKNVAYDHYAPLFTMRLHAELDEGLTKLLKLALNA 445
            ..||.|  :.|.|:.|..|.:.|  |..|: :.:.:    |:..:.....:|:.....||..:|.
Human   372 LTGIILKAAKRFQINIYVKKLDDFVETGDI-RTMVF----PVMYLNESVHIDKETASRLKSMINT 431

  Fly   446 AIIGMYTGIGLVLLGMSIVVTGIFITKKHKW 476
            .:|  .|.|..:::.:     |:|......|
Human   432 TLI--ITNIPYIIMAL-----GVFFGLVFTW 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31741	NP_724088.2	CD36	21..469	CDD:279474	109/455 (24%)
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	108/451 (24%)
		Important for interaction with GBA	155..191		9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930