DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31741 and scarb2b

DIOPT Version :9

Sequence 1:	NP_724088.2	Gene:	CG31741 / 35079	FlyBaseID:	FBgn0051741	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	483	Identity:	117/483 - (24%)
Similarity:	219/483 - (45%)	Gaps:	27/483 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RCGCCSVRQQKIWVFSMGG-----LILAIGIFLASAWPAVSRQWIRSLLPLAPNSFIYNRWVTTP 61
            :..||        ::|.|.     |:..|.:|.:..:..:....::..:.|...|.::..|...|
Zfish     3 KSSCC--------MYSCGAAGALLLLAGIALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPP 59

  Fly    62 TPVYSTVFLFNWTNPGDLNTEGVKPHFEQLGPYTFSDFKVKEDLEW--NQPQVTYFGKRTWHFLP 124
            .|||...|.||.|||........|....::||||:.:::.|.::.:  |..:|..:..:.:.|:|
Zfish    60 PPVYMEFFFFNVTNPEAFLKGEAKARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPKVFVFVP 124

  Fly   125 EKSNGSLD-DVVIAPHFPTLTAALYSRRLRRILRKVMNFTLNREGGATHMTHTAGQWLFDGYYDH 188
            |||.|... |:|...:.|.:......:....::...|:..:...|....||||..:.|: |:.|.
Zfish   125 EKSVGDPSVDMVTTVNIPAVAVMNRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLW-GFKDP 188

  Fly   189 LLDFVEQLHSPLLPVYDNTFGWFYERNNSKTAEGNFTLHTGRGDLSQLGDLLLWNGENTTGFY-P 252
            ||   .:|.| :.|..|..||....:|.|.  :|.|..|||..:....|.:..|.||....|: .
Zfish   189 LL---TKLRS-IKPETDEFFGLMLHKNGSD--DGEFVYHTGEHNYLDYGRIFTWKGEKLMSFWKT 247

  Fly   253 GECGKVNGSTGELWSPYRTWDQPTTIFLPDAARYLNLFPKENLTIDGIDVWRYESTNLTIDNGQL 317
            .:...:||:.|..:.|:.|.::...:|..|..|.:::..::.:.:.||..:|:......:.:|..
Zfish   248 NQSNMINGTDGSAFHPFLTKEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFTPPRAVLASGTN 312

  Fly   318 SPDTECFCLKNRECPRNGVLDYGPPAFNGPFYMSHPHFFLTDQMYRENTTGLQPEESEHGMYVIM 382
            :|:.|.|||..::|..:||||........|..:|.|||.|.|:.|.:...||.|...:|..::.:
Zfish   313 NPENEGFCLTPKKCLDDGVLDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFLDL 377

  Fly   383 EPTLGIPLSLRGQLMISTKVVRDEAIDLFKNVAYDHYAPLFTMRLHAELDE-GLTKLLKLALNAA 446
            .||:|:|:....:..|:..:.|.....:.:|:....: |:..:.....:|. ...::.||.|...
Zfish   378 NPTMGVPVRAMKRAQINIHLERVTGFPMTRNLESTIF-PIIFLNESVVIDNASAERIQKLLLVVT 441

  Fly   447 IIGMYTGIGLVLLGMSIVVTGIFITKKH 474
            ::..:..| ||.||:.:::..:.:..::
Zfish   442 LVSHFPLI-LVALGVILLIVAVILAVRY 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31741	NP_724088.2	CD36	21..469	CDD:279474	113/452 (25%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	110/441 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030