DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31741 and scarb2c

DIOPT Version :9

Sequence 1:	NP_724088.2	Gene:	CG31741 / 35079	FlyBaseID:	FBgn0051741	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001352071.1	Gene:	scarb2c / 337532	ZFINID:	ZDB-GENE-030131-5789	Length:	478	Species:	Danio rerio

Alignment Length:	503	Identity:	126/503 - (25%)
Similarity:	225/503 - (44%)	Gaps:	54/503 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRCGCCSVRQQKIWVFSMGG------LILAIGIFLASAWPAVSRQWIRSLLPLAPNSFIYNRWVT 59
            ||...|.|        |..|      ||..|.:.|......:....::..:.|...:..::.|..
Zfish     1 MRLRLCCV--------STAGALCVLLLICGIALELTRVLQKLVNNTVKQQIVLENGTEAFSVWQN 57

  Fly    60 TPTPVYSTVFLFNWTNPGDLNTEGVKPHFEQLGPYTFSDFKVKEDLEW--NQPQVTYFGKRTWHF 122
            .|.|||...:.||.|||.:: ..|.||...|:||||:.:::..|::::  |..:|.....:|:.|
Zfish    58 PPPPVYMQFYFFNLTNPAEV-MSGDKPSVVQIGPYTYREYRPMEEVKFMDNGTRVAAINPKTYVF 121

  Fly   123 LPEKSNGSLDDVVIAPHFPTLTAALYSRRLRRILRKVMNFTLNREGGATHMTHTAGQWLFDGYYD 187
            .|..|.||.||:|...:.|.:|  :..:....||.::::..:..:|.....|...|..|: ||.|
Zfish   122 EPNMSRGSQDDLVRTVNIPAVT--VMEKYKDSILARLISDLMKAKGVGVFETFRVGDLLW-GYED 183

  Fly   188 HLLDFVEQLHSPLLPVYDNTFGWFYERNNSKTAEGNFTLHTGRGDLSQLGDLLLWNGENTTGFYP 252
            .||   ::||. |:|  |:.||.||::|.  |...::.|.||:.|......:..|||:.:..::.
Zfish   184 PLL---KELHM-LVP--DDHFGLFYKKNG--TEYDSYVLLTGKPDYQDFASIDEWNGQRSLNWWS 240

  Fly   253 G-ECGKVNGSTGELWSPYRTWDQPTTIFLPDAARYLNLFPKENLTIDGIDVWRYESTNLTIDNGQ 316
            . ||..:||:.|..:.|..|......||..|..|.|.:..:.::::.|:..:|:........:..
Zfish   241 SEECNMINGTDGASFHPIITKADRLYIFSSDLCRSLYVQYECDVSVQGVPGFRFVPPADVFSSPD 305

  Fly   317 LSPDTECFCLKNRECPRNGVLDYGPPAFNGPFYMSHPHFFLTDQMYRENTTGLQPEESEHGMYVI 381
            ::||...||:....|..:|:|:........|..||.|||:..||.:.::..|::|.:.||..:..
Zfish   306 INPDNAGFCVPPGHCLGSGLLNASVCKQGAPIIMSSPHFYQADQKFVDDIWGMKPIKEEHQTFAD 370

  Fly   382 MEPTLGIPLSLRGQLMISTKVVRDEAID---LFKNVAYDHYAPLFTMRLHAELD-EGLTKLLKLA 442
            :.|..||.|....::.::..:.:..:..   ..:.:.:    |:..:...|.:| |...||..:.
Zfish   371 INPLTGIVLQGAKRVQVNVYLQQHSSFSQTGKIQTLVF----PVMYINESAFIDEESAKKLHAVV 431

  Fly   443 LNAAIIGMYTGIGLVLLGMSIVVTGIFITKKHKWHSEQRPDKHLQCTQ 490
            |||.::   ..|..:::.:.|::..|||.              |.|.|
Zfish   432 LNANVV---INIPFIVISVGILLGIIFIV--------------LMCRQ 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31741	NP_724088.2	CD36	21..469	CDD:279474	114/454 (25%)
scarb2c	NP_001352071.1	CD36	15..457	CDD:307331	116/460 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920