DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr1 and arr3b

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_957086.1	Gene:	arr3b / 796867	ZFINID:	ZDB-GENE-030616-74	Length:	362	Species:	Danio rerio

Alignment Length:	363	Identity:	136/363 - (37%)
Similarity:	213/363 - (58%)	Gaps:	12/363 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70
            ||:||.|.|..:.||:.||||||.|..|:.:||::.:|...: ..||::|||.|.|||||||.::
Zfish     3 KVYKKTSGNGSLCLYLGRRDFVDHVESVDSVDGVLKIDPSGL-NGRKVWVQLACAFRYGREDLDV 66

  Fly    71 IGLRFQKELTLVSQQVCPPQKQDIQLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASDE 135
            ||:.|:|::.:...|:.|.:......|.|||.||||.|...:||...:|...|.||.||....|.
Zfish    67 IGVSFRKDIWIKRIQMYPFEGTKPPNTPMQEALLKKAGDQGHPFTFDIPVHLPCSVSLQPAPEDA 131

  Fly   136 SQPCGVQYFVKIFTG---DSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELE 197
            .:||||.|.||.:..   |:..::..::.|..|.|||:||||.:....|...:.|.|:.:...:.
Zfish   132 GKPCGVDYEVKAYIANEEDNIDEKVEKKDTCRLIIRKIQYAPAELAAGPKADINKQFITADKPIH 196

  Fly   198 LEVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCP 262
            :||:::|:||:||:.|.:.:.|.|.::|||||||..:.|..|||::...::...:  :....|..
Zfish   197 MEVSMEKELYYHGDPIPIKVKVNNETSKVVKKIKINIFQITDVVIYAADKYHKCV--LNEEFGDQ 259

  Fly   263 LNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVK 327
            :|..|:.:|...:.|.||.|.::.|:|::|.:|.:||.|||:||:.....:...|::|||.:||.
Zfish   260 INANSTFEKEYSVTPLLVNNKEKRGLALDGRLKDEDTNLASSTLLIPDMDKQMQGVVVSYKIKVI 324

  Fly   328 LFLGA--LG----GELCAELPFILMHPKPSRKAQLEAE 359
            |.:|.  ||    .::.||||.:||.|||:..:.:..|
Zfish   325 LMMGGGLLGSLTSSDVTAELPLVLMSPKPAEISDINLE 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	64/158 (41%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	57/163 (35%)
arr3b	NP_957086.1	Arrestin_N	16..172	CDD:278754	64/156 (41%)
arr3b	NP_957086.1	Arrestin_C	192..353	CDD:214976	57/162 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030