DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr1 and saga

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_956853.1	Gene:	saga / 792319	ZFINID:	ZDB-GENE-040426-1538	Length:	392	Species:	Danio rerio

Alignment Length:	358	Identity:	158/358 - (44%)
Similarity:	229/358 - (63%)	Gaps:	8/358 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDD-EM 70
            ||||.|.:..:.:||.:|||||.|..|:|:||:|::|.|.:| .:|.:|.|.|.|||||:|| |:
Zfish     7 VFKKISKDKSVGVYMGKRDFVDRVDSVDPVDGVILIDPEQLR-GKKAYVTLSCVFRYGRDDDAEV 70

  Fly    71 IGLRFQKELTLVSQQVCP--PQKQDIQLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKAS 133
            :|:.|:||:.:.::||.|  ..|:...|||:||:||:|||.|||||..:.|.:.|.||.||....
Zfish    71 LGISFRKEIYISTRQVYPALQDKEQCILTKVQEKLLRKLGDNAYPFFFEFPDNLPCSVGLQPAPK 135

  Fly   134 DESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELEL 198
            |..:.|.|::.||.|..:|...:..:||::.|.||||||||.|.|..|.....:|||:|...|.|
Zfish   136 DVGKHCAVEFEVKAFCAESQDAKVRKRSSVGLMIRKVQYAPEKLGPAPSVETTRDFLMSDKPLHL 200

  Fly   199 EVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPL 263
            |.:|:||.|:|||.|:|.:.:.|.|||.|:.|...|:|..:|||:.|..:...:|..::  |..:
Zfish   201 EASLEKQTYYHGEPINVRVKINNQSNKNVRNIILSVEQNANVVLYCNDNYMKVVATEDS--GHSV 263

  Fly   264 NPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKL 328
            :.|:.|:||..|:|.|..|.:|.|||::|.:|.:||.|||:::|.....::..||:|||.|.|||
Zfish   264 DSGAKLEKVYTLLPLLANNRERRGIALDGKLKHEDTNLASSSIIKEGVQKEVLGIMVSYRVVVKL 328

  Fly   329 FLGALGG--ELCAELPFILMHPKPSRKAQLEAE 359
            .:|.:.|  |:..||||.||||||....:.|||
Zfish   329 IVGGMMGSSEVGVELPFQLMHPKPDAVKESEAE 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	72/158 (46%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	67/159 (42%)
saga	NP_956853.1	Arrestin_N	17..175	CDD:304627	72/158 (46%)
saga	NP_956853.1	Arrestin_C	194..352	CDD:214976	67/159 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930