DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr1 and arr3a

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001002405.1	Gene:	arr3a / 436678	ZFINID:	ZDB-GENE-040718-102	Length:	357	Species:	Danio rerio

Alignment Length:	355	Identity:	137/355 - (38%)
Similarity:	212/355 - (59%)	Gaps:	13/355 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70
            ||:||.|.|..:|||:.:||:||.|..|:.::|.:.:|...: .::|::|||.|.|||||||.::
Zfish     4 KVYKKTSGNGQLTLYLGKRDYVDHVDVVDAVEGAVKIDPADL-GDKKVWVQLACAFRYGREDLDV 67

  Fly    71 IGLRFQKELTLVSQQVCPPQKQDIQLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASDE 135
            |||.|:|::.:...|:.|.......||:|...||||.|...:||...:|.:.|.||.||....|:
Zfish    68 IGLSFRKDIWIQHIQLYPEAGHKPTLTEMHNTLLKKAGEQGHPFTFNIPTNLPCSVTLQPGPDDK 132

  Fly   136 SQPCGVQYFVKIF---TGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELE 197
            .:.|||.:.||.:   :.|...::..::.|..|.|||:|:||...|......:.|.|::|...:.
Zfish   133 GKACGVDFEVKAYVAKSADDPDEKVDKKDTCRLVIRKIQFAPDNTGSGQKAELCKSFMMSDKPVL 197

  Fly   198 LEVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCP 262
            ||.:|:|::|:||:.|.|||.::|.:|||||:|:..|.|..||||:...::...:...|..|...
Zfish   198 LEASLEKEIYYHGDPIPVNIKIKNETNKVVKRIRVTVDQTTDVVLYSADKYTKNVLTEEFGETVE 262

  Fly   263 LNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVK 327
            .|  ||.:|.:.:.|.|..|.::.|:|::|.:|.:||.|||||:|.:...::..||:|||.:||.
Zfish   263 AN--SSFEKSLDITPLLANNKEKRGLALDGRLKDEDTNLASTTIIRTGMDKEMLGILVSYKIKVN 325

  Fly   328 LFL---GALGG----ELCAELPFILMHPKP 350
            |.:   |.|||    ::..|||..||||||
Zfish   326 LMVSGGGLLGGLTASDVTVELPLTLMHPKP 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	59/158 (37%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	65/164 (40%)
arr3a	NP_001002405.1	Arrestin_N	36..173	CDD:304627	50/137 (36%)
arr3a	NP_001002405.1	Arrestin_C	192..355	CDD:214976	65/164 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930